Schizas Nikolaos, Michailidis Theodoros, Samiotis Ilias, Patris Vasilios, Papakonstantinou Konstantinos, Argiriou Michail, Dedeilias Panagiotis
Department of Cardiovascular and Thoracic Surgery, Evangelismos General Hospital, Athens, Greece.
Second Department of Internal Medicine, Hippokration General Hospital of Thessaloniki, Thessaloniki, Greece.
Am J Case Rep. 2020 Sep 27;21:e925931. doi: 10.12659/AJCR.925931.
BACKGROUND The worldwide spread of the severe acute respiratory syndrome-coronavirus-2 (SARS-COV-2) has created unprecedented situations for healthcare professionals and healthcare systems. Although infection with this virus is considered the main health problem currently, other diseases are still prevalent. CASE REPORT This report describes a 59-year-old man who presented with symptoms of dyspnea and fever that were attributed to Covid-19 infection. His clinical condition deteriorated and further examinations revealed a subjacent severe aortic regurgitation due to acute infective endocarditis. Surgical treatment was successful. CONCLUSIONS The results of diagnostic tests for Covid-19 should be re-evaluated whenever there are clinical mismatches or doubts, as false-positive Covid-19 test results can occur. Clinical interpretation should not be determined exclusively by the Covid-19 pandemic. This case report highlights the importance of using validated and approved serological and molecular testing to detect infection with SARS-CoV-2, and to repeat tests when there is doubt about presenting symptoms.
背景 严重急性呼吸综合征冠状病毒2（SARS-CoV-2）在全球范围内的传播给医护人员和医疗系统带来了前所未有的局面。尽管感染这种病毒被认为是当前主要的健康问题，但其他疾病仍然普遍存在。病例报告 本报告描述了一名59岁男性，他出现了呼吸困难和发热症状，最初归因于新冠病毒19（Covid-19）感染。其临床状况恶化，进一步检查发现由于急性感染性心内膜炎导致严重的主动脉瓣反流。手术治疗成功。结论 每当出现临床不匹配或疑问时，都应重新评估Covid-19的诊断测试结果，因为可能会出现Covid-19检测结果假阳性的情况。临床解读不应仅由Covid-19大流行决定。本病例报告强调了使用经过验证和批准的血清学和分子检测来检测SARS-CoV-2感染以及在对呈现的症状存在疑问时重复检测的重要性。
