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关于妊娠相关乳腺癌的误解。

Misconceptions surrounding pregnancy-associated breast cancer.

作者信息

Khalil Nada, Fowler Clare

机构信息

University of Bristol Medical School, Bristol, UK.

Gloucestershire Royal Hospital, Gloucester, UK.

出版信息

BMJ Case Rep. 2018 Dec 17;11(1):e226719. doi: 10.1136/bcr-2018-226719.

DOI:10.1136/bcr-2018-226719
PMID:30567280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6301761/
Abstract

This case report describes a 31-year-old woman who presented with a right painless breast lump. A mammogram and ultrasound scan showed the lump was suspicious of cancer. Core biopsy and immunohistochemistry of the lump confirmed a triple negative, poorly differentiated, invasive ductal carcinoma of the right breast. One week following her diagnosis, the patient found out she was pregnant. The patient was worried about what the implications this diagnosis would have on both her baby and her own cancer treatment.

摘要

本病例报告描述了一名31岁女性,她因右侧乳房无痛性肿块前来就诊。乳房X光检查和超声扫描显示该肿块疑似癌症。肿块的核心活检和免疫组化证实为三阴性、低分化、右侧乳腺浸润性导管癌。确诊一周后,患者发现自己怀孕了。患者担心这一诊断对她的宝宝和自身癌症治疗会有什么影响。

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本文引用的文献

1
Breast cancer and pregnancy.乳腺癌与妊娠
Horm Mol Biol Clin Investig. 2017 Aug 29;32(1):/j/hmbci.2017.32.issue-1/hmbci-2017-0026/hmbci-2017-0026.xml. doi: 10.1515/hmbci-2017-0026.
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Management of Breast Cancer during Pregnancy: Are We Compliant with Current Guidelines?孕期乳腺癌的管理:我们是否遵循当前指南?
AJP Rep. 2017 Jan;7(1):e39-e43. doi: 10.1055/s-0037-1599133.
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Triple Negative Breast Cancer in Pregnancy and Postpartum: Two Case Reports in Hispanic Women.孕期及产后三阴性乳腺癌:两例西班牙裔女性病例报告
Case Rep Obstet Gynecol. 2015;2015:856931. doi: 10.1155/2015/856931. Epub 2015 Sep 13.
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Breast cancer in pregnancy.妊娠期乳腺癌。
Obstet Gynecol Clin North Am. 2013 Sep;40(3):559-71. doi: 10.1016/j.ogc.2013.05.006. Epub 2013 Jul 30.
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[Breast cancer during pregnancy and chemotherapy: a systematic review].
Rev Assoc Med Bras (1992). 2013 Mar-Apr;59(2):174-80. doi: 10.1016/j.ramb.2012.10.003.
6
Ondansetron in pregnancy and risk of adverse fetal outcomes.妊娠期应用昂丹司琼与不良胎儿结局风险。
N Engl J Med. 2013 Feb 28;368(9):814-23. doi: 10.1056/NEJMoa1211035.
7
Treatment of breast cancer during pregnancy: an observational study.妊娠期乳腺癌的治疗:一项观察性研究。
Lancet Oncol. 2012 Sep;13(9):887-96. doi: 10.1016/S1470-2045(12)70261-9. Epub 2012 Aug 16.
8
Being Pregnant and Diagnosed with Breast Cancer.怀孕且被诊断出患有乳腺癌。
Breast Care (Basel). 2012 Jun;7(3):204-209. doi: 10.1159/000339674. Epub 2012 Jun 27.
9
Breast cancer in pregnancy.妊娠期乳腺癌。
Lancet. 2012 Feb 11;379(9815):570-9. doi: 10.1016/S0140-6736(11)61092-1.
10
Characteristics of triple-negative breast cancer in patients with a BRCA1 mutation: results from a population-based study of young women.BRCA1 突变患者中三阴性乳腺癌的特征:一项基于人群的年轻女性研究结果。
J Clin Oncol. 2011 Nov 20;29(33):4373-80. doi: 10.1200/JCO.2010.33.6446. Epub 2011 Oct 17.