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三维超声产前诊断合并丹迪-沃克囊肿疝出胎儿的颈肋

Prenatal diagnosis of cervical ribs by three-dimensional ultrasound in a foetus with a herniated Dandy-Walker cyst.

作者信息

Schut Pauline, Verdijk Robert M, Joosten Marieke, Eggink Alex J

机构信息

Prenatal Medicine, Erasmus MC, Rotterdam, The Netherlands.

Department of Pathology, Erasmus MC, Rotterdam, The Netherlands.

出版信息

BMJ Case Rep. 2018 Dec 18;11(1):e225381. doi: 10.1136/bcr-2018-225381.

DOI:10.1136/bcr-2018-225381
PMID:30567892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6303663/
Abstract

We present a case report of a foetus with a herniated Dandy-Walker cyst and bilateral rudimentary cervical ribs. The cervical ribs were visualised prenatally by three-dimensional ultrasound and confirmed by post-termination radiography. The prevalence of cervical ribs is higher in deceased fetuses and neonates with or without structural abnormalities compared with healthy individuals and might be regarded as a marker of disadvantageous fetal development. We demonstrate that evaluation of the fetal vertebral pattern by three-dimensional ultrasonography, including the cervical region, is feasible and could provide valuable information regarding fetal and neonatal prognosis.

摘要

我们报告一例患有丹迪-沃克囊肿疝和双侧颈椎肋骨发育不全的胎儿病例。颈椎肋骨在产前通过三维超声得以显示,并在终止妊娠后的X光检查中得到证实。与健康个体相比,颈椎肋骨在有或无结构异常的死胎和新生儿中更为常见,可能被视为胎儿发育不利的一个标志。我们证明,通过三维超声检查评估胎儿的椎体形态,包括颈椎区域,是可行的,并且可以提供有关胎儿和新生儿预后的有价值信息。

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BMJ Case Rep. 2018 Dec 18;11(1):e225381. doi: 10.1136/bcr-2018-225381.
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本文引用的文献

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Increased prevalence of abnormal vertebral patterning in fetuses and neonates with trisomy 21.21三体胎儿和新生儿中异常椎体模式的患病率增加。
J Matern Fetal Neonatal Med. 2019 Jul;32(14):2280-2286. doi: 10.1080/14767058.2018.1431622. Epub 2018 Feb 5.
2
Adverse Fetal and Neonatal Outcome and an Abnormal Vertebral Pattern: A Systematic Review.不良胎儿和新生儿结局与异常椎体模式:系统评价。
Obstet Gynecol Surv. 2016 Dec;71(12):741-750. doi: 10.1097/OGX.0000000000000388.
3
Evo-Devo of the Human Vertebral Column: On Homeotic Transformations, Pathologies and Prenatal Selection.人类脊柱的演化发育生物学:同源异型转化、病理学与产前选择
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3D/4D ultrasound in prenatal diagnosis: is it time for routine use?三维/四维超声在产前诊断中的应用:是时候常规使用了吗?
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Cervical ribs are more prevalent in stillborn fetuses than in live-born infants and are strongly associated with fetal aneuploidy.颈肋在死产胎儿中比在活产婴儿中更常见,并且与胎儿非整倍体密切相关。
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Three-dimensional ultrasound in evaluating the fetus.三维超声在胎儿评估中的应用。
Prenat Diagn. 2010 Jul;30(7):631-8. doi: 10.1002/pd.2561.
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Hox genes and regional patterning of the vertebrate body plan.Hox 基因与脊椎动物身体模式的区域构成。
Dev Biol. 2010 Aug 1;344(1):7-15. doi: 10.1016/j.ydbio.2010.04.024. Epub 2010 May 7.
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Extreme selection in humans against homeotic transformations of cervical vertebrae.人类对颈椎同源异型转化的极端选择。
Evolution. 2006 Dec;60(12):2643-54.