Department of Neurology, Hangzhou Red Cross Hospital, Hangzhou, China.
Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China,
Clin Interv Aging. 2018 Nov 27;13:2421-2424. doi: 10.2147/CIA.S186636. eCollection 2018.
Few cases of mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) with an onset older than 60 years have been reported. Herein, we report a 63-year-old Chinese female initially suspected of ischemic infarction but was ultimately diagnosed with MELAS. Therefore, even in the elderly, a diagnosis of MELAS should be considered when encountering patients with recurrent stroke-like episodes, cognitive dysfunction, and psychotic symptoms. In order to achieve the correct diagnosis and launch the appropriate management in time, a detailed medical history together with appropriate diagnostic laboratory investigations should therefore be collected.
已有少数报道称，线粒体脑肌病伴高乳酸血症和卒中样发作（MELAS）的发病年龄大于 60 岁。在此，我们报告了一例 63 岁的中国女性，最初疑似缺血性梗死，但最终被诊断为 MELAS。因此，即使在老年人中，当遇到反复发生卒中样发作、认知功能障碍和精神病症状的患者时，也应考虑 MELAS 的诊断。为了达到正确的诊断并及时采取适当的治疗，因此应收集详细的病史和进行适当的诊断性实验室检查。
