妊娠合并线粒体脑肌病伴乳酸血症和卒中样发作（MELAS）综合征
Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome in pregnancy.
作者信息
Balachandran Nair Deepa, Bloomfield Mariana, Parasuraman Rajeswari, Howe David T
机构信息
Department of Obstetrics and Gynaecology, Stoke Mandeville Hospital, Aylesbury, UK
Department of Obstetrics and Gynaecology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
出版信息
BMJ Case Rep. 2021 Apr 7;14(4):e235111. doi: 10.1136/bcr-2020-235111.
The syndrome of mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) is a rare mitochondrial disease with few documented cases in pregnancy. In this case report, we discuss the presentation and management of a 39-year-old grand multiparous lady with MELAS syndrome, which was diagnosed prior to her eighth pregnancy, discuss potential implications of the condition in pregnancy and summarise the current guidelines for the management of this rare condition.
线粒体脑肌病伴乳酸酸中毒及卒中样发作综合征（MELAS）是一种罕见的线粒体疾病，孕期有记录的病例很少。在本病例报告中，我们讨论了一位39岁、有多次分娩史且患有MELAS综合征的女性患者的临床表现及治疗情况，该患者在第八次怀孕前被诊断为此病，探讨了该病症在孕期的潜在影响，并总结了目前针对这种罕见病症的治疗指南。
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