van Balkum M, Kluin-Nelemans H, van Hellemond J J, van Genderen P J J, Wismans P J
Harbour Hospital and Institute for Tropical Diseases, Rotterdam, the Netherlands (currently working at Albert Schweitzer Hospital, Rotterdam).
Neth J Med. 2018 Dec;76(10):431-436.
Hypereosinophilia encompasses a broad differential diagnosis of atopy/allergic reactions, drug reactions, parasitic infections and paraneoplastic syndromes. Although mostly of limited clinical significance, hypereosinophilia can also be related to hematological malignancies. One has to be aware of the potential for secondary organ damage for example, in the case of hypereosinophilic syndrome. We present three cases with different underlying mechanisms of hypereosinophilia with a brief overview of causes, diagnostic work-up and treatment options.
嗜酸性粒细胞增多症涵盖了多种不同的诊断,包括特应性/过敏反应、药物反应、寄生虫感染和副肿瘤综合征。尽管嗜酸性粒细胞增多症大多临床意义有限,但它也可能与血液系统恶性肿瘤有关。必须意识到存在继发性器官损伤的可能性,例如在嗜酸性粒细胞增多综合征的情况下。我们介绍三例嗜酸性粒细胞增多症潜在机制不同的病例,并简要概述其病因、诊断检查和治疗选择。