Abdullah Nasturah, Baharudin Noorhida, Mohd Rustam Farah Roslinda, Khalid Zalizah
Department of Primary Care Medicine, Faculty of Medicine, Universiti Teknologi MARA, Selayang Campus, Batu Caves 68100, Malaysia.
Department of Medical Microbiology and Parasitology, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh 47000, Malaysia.
Clin Pract. 2021 Oct 26;11(4):785-790. doi: 10.3390/clinpract11040094.
Eosinophilic leukocytosis can be attributed to a number of clinical conditions such as parasitic infection, allergies, and neoplasms. Parasitic infection is the main cause of eosinophilia; however, a marked leukocytosis with hypereosinophilia secondary to in adults has not been previously reported. We describe a case of a 39-year-old man who presented with fever and diarrhea. The investigation revealed a white blood cell (WBC) count of 20.69 × 10/L with an absolute eosinophil count of 12.44 × 10/L. Fecal microscopic examination demonstrated eggs. The WBC count returned to normal following treatment with albendazole. The literature pertaining to hematological findings associated with is explored in this report. This case highlights that a significant elevation of leukocyte count with hypereosinophilia can be one of the manifestations of trichuriasis infection in adults. Empirical treatment with anti-helminthic agents may play a role in suspected cases to avoid severe complications, such as Trichuris dysentery syndrome.
嗜酸性粒细胞增多症可归因于多种临床病症,如寄生虫感染、过敏和肿瘤。寄生虫感染是嗜酸性粒细胞增多的主要原因;然而,成人继发于[此处原文缺失相关内容]的显著白细胞增多伴嗜酸性粒细胞增多症此前尚未见报道。我们描述了一例39岁男性患者,其表现为发热和腹泻。检查发现白细胞(WBC)计数为20.69×10⁹/L,绝对嗜酸性粒细胞计数为12.44×10⁹/L。粪便显微镜检查发现了[此处原文缺失相关虫卵名称]虫卵。使用阿苯达唑治疗后白细胞计数恢复正常。本报告探讨了与[此处原文缺失相关内容]相关的血液学检查结果的文献。该病例突出表明,白细胞计数显著升高伴嗜酸性粒细胞增多可能是成人鞭虫感染的表现之一。对于疑似病例,经验性使用抗蠕虫药物治疗可能有助于避免严重并发症,如鞭虫痢疾综合征。