Brett M T, Kwan J T, Bending M R
Department of Histopathology, St Helier Hospital, Carshalton, Surrey.
J Clin Pathol. 1988 Sep;41(9):992-5. doi: 10.1136/jcp.41.9.992.
A renal transplant patient developed a fatal caecal perforation after Histoplasma capsulatum infection acquired abroad. Disseminated histoplasmosis is an uncommon fungal infection, usually seen in patients with impaired immunity. The diagnosis should be considered in immunosuppressed patients who develop prolonged fever or whose health deteriorates unexpectedly after travelling overseas. The infection is endemic in parts of the United States of America but occurs all over the world. Rapid diagnosis is often possible by histological examination of infected tissues. Treatment if started early may lead to recovery, but if it is not treated it is usually fatal.
一名肾移植患者在国外感染荚膜组织胞浆菌后发生致命的盲肠穿孔。播散性组织胞浆菌病是一种罕见的真菌感染，通常见于免疫功能受损的患者。对于出现长期发热或在海外旅行后健康状况意外恶化的免疫抑制患者，应考虑该病的诊断。这种感染在美国部分地区为地方病，但在全世界都有发生。通过对感染组织进行组织学检查通常可以快速诊断。如果早期开始治疗可能会康复，但如果不治疗通常会致命。
