Park Sung Wook, Kim Youngsoon, Kang Hee Yong, You Ann Hee, Jeon Jong Mi, Woo Hyunho, Choi Jeong-Hyun
Department of Anesthesiology and Pain Medicine, College of Medicine, Kyung Hee University, Seoul, Korea.
Medicine (Baltimore). 2018 Dec;97(51):e13863. doi: 10.1097/MD.0000000000013863.
Radiofrequency ablation (RFA) has become the reliable, effective, and less invasive treatment for small primary or metastatic hepatic tumors. Hepatic tumors that located immediately beneath the diaphragm are difficult to treat with percutaneous RFA due to poor visualization by percutaneous ultrasonography and the close location of the heart or lung. A transthoracic approach has been proposed to be an alternative for hepatic tumors located beneath the diaphragm that are difficult to access by conventional percutaneous or laparoscopic approaches. There has been no report regarding the anesthetic management of the transthoracic RFA for hepatic tumor.
A 69-year-old female had undergone segmentectomy due to hepatocellular carcinoma 4 years ago.
Newly developed hepatic tumor located in the liver dome and beneath the diaphragm was diagnosed by follow-up imaging study.
Because the tumor could not be identified by transabdominal ultrasonography (US), transthoracic approach for RFA under one-lung ventilation was planned. General anesthesia was induced with propofol and remifentanil via target-controlled infusion system and rocuronium was administered. Orotracheal intubation with double-lumen endotracheal tube was performed and position of the tube in the trachea was confirmed by bronchoscope. The RFA electrode was introduced percutaneously into the right pleural cavity, guided by visualization through the thoracoscope and inserted into the tumor after visualizing the tumor by US. Radiofrequency waves can be successfully administered through the needle.
We performed successfully RFA of the hepatic tumor through one-lung ventilation and transthoracic approach. At 5 days postoperatively, she was discharged in a stable condition without any complication.
Transthoracic RFA can be successfully performed under one-lung ventilation, optimal analgesia, and vigilant monitoring.
射频消融术(RFA)已成为治疗小的原发性或转移性肝肿瘤的可靠、有效且侵入性较小的方法。由于经皮超声检查可视化效果不佳以及心脏或肺部位置较近,位于膈肌正下方的肝肿瘤难以通过经皮RFA进行治疗。对于位于膈肌下方、难以通过传统经皮或腹腔镜方法处理的肝肿瘤,已提出经胸入路作为一种替代方法。目前尚无关于肝肿瘤经胸RFA麻醉管理的报道。
一名69岁女性4年前因肝细胞癌接受了肝段切除术。
通过随访影像学检查诊断为新出现的位于肝穹窿部和膈肌下方的肝肿瘤。
由于经腹部超声(US)无法识别肿瘤,计划在单肺通气下采用经胸入路进行RFA。通过靶控输注系统用丙泊酚和瑞芬太尼诱导全身麻醉,并给予罗库溴铵。插入双腔气管导管进行经口气管插管,并通过支气管镜确认导管在气管内的位置。在胸腔镜可视化引导下,经皮将RFA电极引入右胸腔,并在超声显示肿瘤后插入肿瘤内。可通过针成功施加射频波。
我们通过单肺通气和经胸入路成功对肝肿瘤进行了RFA。术后5天,她病情稳定出院,无任何并发症。
经胸RFA可在单肺通气、最佳镇痛和密切监测下成功进行。