视神经成血管细胞瘤：慢性体征
Optic Nerve Haemangioblastoma: Signs of Chronicity.
作者信息
McGrath Lindsay A, Mudhar Hardeep Singh, Salvi Sachin M
机构信息
University of Queensland School of Medicine, Brisbane, Queensland, Australia.
Sheffield Ocular Oncology Service, Royal Hallamshire Hospital, Sheffield, United Kingdom.
出版信息
Ocul Oncol Pathol. 2018 Nov;4(6):370-374. doi: 10.1159/000486863. Epub 2018 Feb 23.
Abstract
Optic nerve haemangioblastomas remain exceedingly rare extrinsic tumours of the optic nerve, often associated with von Hippel-Lindau disease. The authors report a 25-year-old female with a slowly progressive unilateral optic nerve lesion, causing reduced vision and bilateral optic tract oedema. A diagnosis of optic nerve haemangioblastoma with piloid gliosis was made histologically after surgical resection. This is the first reported case of such dual pathology occurring in the optic nerve. The patient has been monitored without further adjuvant treatment, and has not had a recurrence to date, at 6 years of follow-up.
摘要
视神经血管母细胞瘤仍然是极其罕见的视神经外部肿瘤，常与冯·希佩尔-林道病相关。作者报告了一名25岁女性，患有缓慢进展的单侧视神经病变，导致视力下降和双侧视束水肿。手术切除后经组织学诊断为伴有毛细胞性胶质增生的视神经血管母细胞瘤。这是首次报道的视神经出现这种双重病理情况的病例。该患者未接受进一步辅助治疗，目前已随访6年，尚未复发。
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本文引用的文献
1
Optic Nerve Hemangioblastomas?A Review of Visual Outcomes.视神经血管母细胞瘤？视觉预后综述。
Turk Neurosurg. 2017;27(5):827-831. doi: 10.5137/1019-5149.JTN.16680-15.1.
2
Optic nerve hemangioblastoma: a case report.视神经血管母细胞瘤：一例报告。
Case Rep Pathol. 2012;2012:915408. doi: 10.1155/2012/915408. Epub 2012 Apr 24.
3
Gliosis versus glioma?: don't grade until you know.胶质增生与胶质瘤？：在明确诊断前先不要分级。
Adv Anat Pathol. 2012 Jul;19(4):239-49. doi: 10.1097/PAP.0b013e31825c6a04.
4
Progressive peritumoral edema defining the optic fibers and resulting in reversible visual loss.逐渐进展的肿瘤周围水肿界定了视神经纤维，并导致可逆性视力丧失。
J Neurosurg. 2008 Aug;109(2):313-7. doi: 10.3171/JNS/2008/109/8/0313.
5
Clinical course of retrobulbar hemangioblastomas in von Hippel-Lindau disease.冯·希佩尔-林道病中球后成血管细胞瘤的临床病程
Ophthalmology. 2008 Aug;115(8):1382-9. doi: 10.1016/j.ophtha.2008.01.027. Epub 2008 Apr 8.
6
Long-term natural history of hemangioblastomas in patients with von Hippel-Lindau disease: implications for treatment.冯·希佩尔-林道病患者血管母细胞瘤的长期自然病史：对治疗的启示
J Neurosurg. 2006 Aug;105(2):248-55. doi: 10.3171/jns.2006.105.2.248.
7
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Arch Soc Esp Oftalmol. 2006 May;81(5):293-6. doi: 10.4321/s0365-66912006000500009.
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10
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J Neurosurg. 2003 Jan;98(1):82-94. doi: 10.3171/jns.2003.98.1.0082.
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