Lam Michelle S, Fitzpatrick Annette L, Shrestha Archana, Karmacharya Biraj M, Koju Rajendra, Rao Deepa
University of Washington, Department of Global Health.
University of Washington, Department of Medicine, School of Medicine.
Int J Noncommun Dis. 2017;2(1):18-26. doi: 10.4103/jncd.jncd_34_16.
Nepal is currently experiencing a rapid growth in non-communicable diseases (NCDs). Depression has previously been associated with NCDs in South Asia; however, data regarding its prevalence and risk factors is lacking in Nepal.
This study aims to describe the prevalence of and risk factors for depressive symptoms in a suburban population of adults within Nepal.
We conducted a cross-sectional analysis of baseline data collected from participants enrolled in the Dhulikhel Heart Study (DHS), a population-based, longitudinal cohort study investigating cardiovascular risk factors in Dhulikhel, a suburban town outside Kathmandu.
Baseline questionnaire data from 1,073 adults age 18 years and older included the Center for Epidemiologic Studies Depression Scale (CESD). A score of 16 or greater on the CESD has been shown to indicate major depressive symptomatology.
Using STATA 13 we conducted Pearson's chi-squared tests and multiple logistic regressions to examine associations between the binary CESD score and gender, age, education, marital status, body mass index (BMI), physical activity, and hypertensive status.
The mean CESD score in the sample was 11.7 (SD: 5.3), with 21.3% scoring 16 or greater. Age over 60 and lack of formal education were associated with increased risk of depressive symptoms. Being physically active was associated with decreased risk of depressive symptoms.
The estimated prevalence of depression among adults in Dhulikhel was 21.3%. Significant risk factors for increased depressive symptoms included lack of formal education, age over 60, and physical inactivity.
尼泊尔目前正经历非传染性疾病（NCDs）的快速增长。此前在南亚，抑郁症一直与非传染性疾病有关；然而，尼泊尔缺乏关于其患病率和风险因素的数据。
本研究旨在描述尼泊尔郊区成年人群中抑郁症状的患病率及其风险因素。
我们对从参与杜利凯尔心脏研究（DHS）的参与者收集的基线数据进行了横断面分析，DHS是一项基于人群的纵向队列研究，调查加德满都郊外的郊区城镇杜利凯尔的心血管危险因素。
来自1073名18岁及以上成年人的基线问卷数据包括流行病学研究中心抑郁量表（CESD）。CESD得分16分或更高已被证明表明存在重度抑郁症状。
我们使用STATA 13进行了Pearson卡方检验和多重逻辑回归，以检验二元CESD得分与性别、年龄、教育程度、婚姻状况、体重指数（BMI）、身体活动和高血压状态之间的关联。
样本中的CESD平均得分为11.7（标准差：5.3），21.3%的得分在16分或更高。60岁以上和未接受正规教育与抑郁症状风险增加有关。身体活跃与抑郁症状风险降低有关。
杜利凯尔成年人中抑郁症的估计患病率为21.3%。抑郁症状增加的重要风险因素包括未接受正规教育、60岁以上和身体不活动。
