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The Need for Policy Change Regarding Progestin-Only Injectable Contraceptives.关于仅含孕激素的注射用避孕药的政策变革需求。
J Womens Health (Larchmt). 2019 Sep;28(9):1180-1184. doi: 10.1089/jwh.2018.7284. Epub 2018 Dec 21.
2
Update to U.S. Medical Eligibility Criteria for Contraceptive Use, 2016: Updated Recommendations for the Use of Contraception Among Women at High Risk for HIV Infection.美国避孕方法医学资格标准更新，2016 年：艾滋病毒感染高危妇女避孕方法使用的最新建议。
MMWR Morb Mortal Wkly Rep. 2020 Apr 10;69(14):405-410. doi: 10.15585/mmwr.mm6914a3.
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Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study.南非女性中仅含注射用孕激素的避孕药与HIV感染及女性生殖道HIV靶细胞频率之间的关联：一项前瞻性队列研究
Lancet Infect Dis. 2016 Apr;16(4):441-8. doi: 10.1016/S1473-3099(15)00429-6. Epub 2015 Dec 24.
4
Exogenous progestins and breast cancer.外源性孕激素与乳腺癌
Epidemiol Rev. 1993;15(1):98-107. doi: 10.1093/oxfordjournals.epirev.a036120.
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Changes to the World Health Organization guideline on hormonal contraceptive eligibility for women at high risk of HIV: South African perspective and response.世界卫生组织关于艾滋病毒高风险女性激素避孕资格指南的修订：南非视角与应对措施
S Afr Med J. 2018 Jul 25;108(8):629-631. doi: 10.7196/SAMJ.2018.v108i8.13160.
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Progestin-based contraception regimens modulate expression of putative HIV risk factors in the vaginal epithelium of pig-tailed Macaques.基于孕激素的避孕方案可调节猪尾猕猴阴道上皮中潜在 HIV 风险因素的表达。
Am J Reprod Immunol. 2018 Oct;80(4):e13029. doi: 10.1111/aji.13029. Epub 2018 Aug 3.
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Pharmacokinetic, biologic and epidemiologic differences in MPA- and NET-based progestin-only injectable contraceptives relative to the potential impact on HIV acquisition in women.基于 MPA 和 NET 的孕激素避孕药与 HIV 获得的潜在影响相关的药代动力学、生物学和流行病学差异。
Contraception. 2019 Apr;99(4):199-204. doi: 10.1016/j.contraception.2018.12.001. Epub 2018 Dec 18.
8
Ectopic pregnancy with use of progestin-only injectables and contraceptive implants: a systematic review.使用仅含孕激素的注射剂和避孕植入物与异位妊娠：一项系统评价。
Contraception. 2015 Dec;92(6):514-22. doi: 10.1016/j.contraception.2015.08.016. Epub 2015 Sep 10.
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Hormonal Contraception and HIV-1 Acquisition: Biological Mechanisms.激素避孕与 HIV-1 感染：生物学机制。
Endocr Rev. 2018 Feb 1;39(1):36-78. doi: 10.1210/er.2017-00103.
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Association between the use of hormonal contraceptives and risk of cholecystectomy in women of reproductive age.激素避孕药的使用与育龄妇女胆囊切除术风险之间的关联。
Eur J Clin Pharmacol. 2021 Oct;77(10):1523-1529. doi: 10.1007/s00228-021-03137-6. Epub 2021 May 10.

引用本文的文献

1
Medroxyprogesterone Acetate (MPA) Enhances HIV-1 Accumulation and Release in Primary Cervical Epithelial Cells by Inhibiting Lysosomal Activity.醋酸甲羟孕酮（MPA）通过抑制溶酶体活性增强HIV-1在原代宫颈上皮细胞中的积累和释放。
Pathogens. 2021 Sep 14;10(9):1192. doi: 10.3390/pathogens10091192.
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Is the Injectable Contraceptive Depo-Medroxyprogesterone Acetate (DMPA-IM) Associated with an Increased Risk for HIV Acquisition? The Jury Is Still Out.注射用避孕药醋酸甲羟孕酮（DMPA-IM）会增加感染艾滋病毒的风险吗？尚无定论。
AIDS Res Hum Retroviruses. 2020 May;36(5):357-366. doi: 10.1089/AID.2019.0228. Epub 2020 Jan 22.

本文引用的文献

1
Use of contraceptive depot medroxyprogesterone acetate is associated with impaired cervicovaginal mucosal integrity.使用避孕药物醋酸甲羟孕酮长效注射剂会损害宫颈阴道黏膜的完整性。
J Clin Invest. 2018 Oct 1;128(10):4622-4638. doi: 10.1172/JCI120583. Epub 2018 Sep 17.
2
A randomised trial of a contraceptive vaginal ring in women at risk of HIV infection in Rwanda: Safety of intermittent and continuous use.卢旺达感染艾滋病毒风险妇女用避孕阴道环的一项随机试验：间断使用和连续使用的安全性。
PLoS One. 2018 Jun 1;13(6):e0197572. doi: 10.1371/journal.pone.0197572. eCollection 2018.
3
Lessons learnt from the introduction of the contraceptive implant in South Africa.从南非引入避孕植入物中吸取的经验教训。
S Afr Med J. 2017 Oct 1;107(11):933-938. doi: 10.7196/SAMJ.2017.v107i11.12805.
4
Introduction of the contraceptive implant in South Africa: Successes, challenges and the way forward.南非避孕植入剂的引入：成就、挑战与未来之路
S Afr Med J. 2017 Oct 1;107(10):812-814. doi: 10.7196/samj.2017.v107i10.12849.
5
Hormonal Contraception and HIV-1 Acquisition: Biological Mechanisms.激素避孕与 HIV-1 感染：生物学机制。
Endocr Rev. 2018 Feb 1;39(1):36-78. doi: 10.1210/er.2017-00103.
6
From Research to Policy: The WHO Experience With Developing Guidelines on the Potential Risk of HIV Acquisition and Progestogen-Only Contraception Use.从研究到政策：世界卫生组织在制定关于潜在 HIV 获得风险和单纯孕激素避孕方法使用的指南方面的经验。
Glob Health Sci Pract. 2017 Dec 28;5(4):540-546. doi: 10.9745/GHSP-D-17-00278.
7
Update to CDC's U.S. Medical Eligibility Criteria for Contraceptive Use, 2016: Revised Recommendations for the Use of Hormonal Contraception Among Women at High Risk for HIV Infection.《美国疾病控制与预防中心（CDC）2016年避孕方法医学适用标准更新：针对HIV感染高危女性使用激素避孕的修订建议》
MMWR Morb Mortal Wkly Rep. 2017 Sep 22;66(37):990-994. doi: 10.15585/mmwr.mm6637a6.
8
Hormonal contraceptive methods and HIV: research gaps and programmatic priorities.激素避孕方法与艾滋病病毒：研究空白与规划重点
Contraception. 2017 Aug;96(2):67-71. doi: 10.1016/j.contraception.2017.05.015. Epub 2017 Jun 7.
9
An updated systematic review of epidemiological evidence on hormonal contraceptive methods and HIV acquisition in women.关于激素避孕方法与女性感染艾滋病毒情况的流行病学证据的最新系统评价。
AIDS. 2016 Nov 13;30(17):2665-2683. doi: 10.1097/QAD.0000000000001228.
10
Realizing Reproductive Health Equity Needs More Than Long-Acting Reversible Contraception (LARC).实现生殖健康公平所需的不止长效可逆避孕法（LARC）。
Am J Public Health. 2016 Jan;106(1):18-9. doi: 10.2105/AJPH.2015.302900. Epub 2015 Nov 12.

The Need for Policy Change Regarding Progestin-Only Injectable Contraceptives.

作者信息

Gollub Erica L, Jones Heidi E, Ralph Lauren J, van de Wijgert Janneke H H M, Padian Nancy, Stein Zena

机构信息

Health Science Program, College of Health Professions, Pace University, Pleasantville, New York.

Department of Epidemiology and Biostatistics, City University of New York (CUNY) School of Public Health, New York, New York.

出版信息

J Womens Health (Larchmt). 2019 Sep;28(9):1180-1184. doi: 10.1089/jwh.2018.7284. Epub 2018 Dec 21.

DOI:10.1089/jwh.2018.7284
PMID:30576259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6909683/
Abstract
摘要