a Wound Healing and Cell Biology Laboratory, Institute of Basic Medicine Science, College of Life Science , Chinese PLA General Hospital , Beijing , People's Republic of China.
b Key Laboratory of Tissue Repair and Regeneration of PLA and Beijing Key Research Laboratory of Skin Injury, Repair and Regeneration , First Hospital Affiliated to General Hospital of PLA , Beijing , China.
Expert Opin Biol Ther. 2019 Feb;19(2):119-128. doi: 10.1080/14712598.2019.1559290. Epub 2019 Jan 7.
With the continued focus on in-depth investigations of hair follicle stem cells (HFSCs), the role of HFSCs in wound healing has attracted increasing attention from researchers. This review may afford meaningful implications for HFSC treatment of wounds.
We present the properties of HFSCs, analyze the possibility of HFSCs in wound healing, and sum up the recent studies into wound repair with HFSCs. The details of HFSCs in wound healing have been discussed. The possible mechanisms of wound healing with HFSCs have been elaborated. Additionally, the factors that influence HFSCs in wound healing are also summarized.
Hair follicle stem cells are promising sources for wound healing. However, a further understanding of human HFSCs and the safety use of HFSCs in clinical practice still remain in relative infancy.
随着对毛囊干细胞（HFSCs）深入研究的持续关注，HFSCs 在伤口愈合中的作用引起了研究人员的越来越多的关注。本综述可能为 HFSC 治疗伤口提供有意义的启示。
我们介绍了 HFSCs 的特性，分析了 HFSCs 在伤口愈合中的可能性，并总结了 HFSCs 用于伤口修复的最新研究。讨论了 HFSCs 在伤口愈合中的详细作用机制。阐述了 HFSCs 促进伤口愈合的可能机制。此外，还总结了影响 HFSCs 在伤口愈合中的因素。
毛囊干细胞是伤口愈合有前途的来源。然而，对人类 HFSCs 的进一步了解以及 HFSCs 在临床实践中的安全应用仍处于相对初期阶段。
