Karal'nik B V, Li V P, Denisov G I
Zh Mikrobiol Epidemiol Immunobiol. 1988 Aug(8):39-44.
1,390 samples of different excreta obtained from salmonellosis patients have been tested for the presence of S. typhimurium O- and H-antigens. S. typhimurium antigens, detected with the use of antibody diagnostica, have been found to occur more frequently than S. typhimurium cells. Particulate O- and H-antigens capable of agglutinating antibody diagnostica are excreted differently with saliva and urine. Salmonella antigens are best detected in feces in the passive hemagglutination test with the use of antibody diagnostica, but not in the antibody neutralization test. The combination of the passive hemagglutination test, carried out with the use of antibody diagnostica, and bacteriological study considerably enhances the efficiency of diagnosing salmonellosis in children in comparison with bacteriological study alone.
对1390份从沙门氏菌病患者身上获取的不同排泄物样本进行了鼠伤寒沙门氏菌O抗原和H抗原检测。通过使用诊断性抗体检测发现，鼠伤寒沙门氏菌抗原的出现频率高于鼠伤寒沙门氏菌细胞。能够凝集诊断性抗体的颗粒状O抗原和H抗原通过唾液和尿液的排泄方式不同。在使用诊断性抗体的被动血凝试验中，粪便中沙门氏菌抗原最易检测到，但在抗体中和试验中则不然。与单独的细菌学研究相比，使用诊断性抗体进行的被动血凝试验与细菌学研究相结合，大大提高了儿童沙门氏菌病的诊断效率。
