J Med Ethics. 2019 Feb;45(2):144-145. doi: 10.1136/medethics-2018-105268. Epub 2018 Dec 22.
In terms of ethical implications, Boers, van Delden and Bredenoord (2018) have made an interesting step forward with their model of organoids as hybrids, which seeks to find a balance between subject-like value and object-like value. Their framework aims to introduce effective procedures not to exploit donors and to increase their engagement, but it does not seem to take sufficient account of how organoids are used and how donors and society as a whole may want to act about such uses. I will concentrate my remarks on three points that I consider relevant. The first comment concerns the so-called mini-brains. The second one is related to the issue of consent and long-term 'control' over the organic material granted by donors. The last comment focuses on 'genetic minorities'.
就伦理影响而言，Boers、van Delden 和 Bredenoord（2018）在他们的类器官杂交模型方面迈出了有趣的一步，该模型试图在主体价值和客体价值之间找到平衡。他们的框架旨在引入有效的程序，以防止剥削供体并提高他们的参与度，但似乎没有充分考虑到类器官的使用方式以及供体和整个社会可能希望对此类用途采取的行动。我将集中讨论我认为相关的三个要点。第一个评论涉及所谓的迷你大脑。第二个与同意的问题以及供体授予的有机材料的长期“控制”有关。最后一个评论集中在“遗传少数群体”上。
