Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, People's Republic of China.
J Bone Miner Res. 2012 Jan;27(1):125-9. doi: 10.1002/jbmr.519.
The age-specific rates of hip fractures have been declining in most countries in the West but a few studies suggest that the rates might be increasing in areas of Asia that are undergoing urbanization. We previously conducted a population-based study of hip fracture rates in Beijing, China, in 1990 to 1992 that included validation of hip fracture cases. Using a similar approach to validate cases, we estimated the age-specific hip fracture rates in Beijing, China, for 2002 to 2006. Specifically, we obtained hospital discharge data for hip fractures that were reported to the Beijing Bureau of Public Health. To confirm the diagnoses, Beijing residence, and find cases missed by the public records we checked individual cases in the public health records against medical records in a random sample of Beijing hospitals. The rates from public health data were adjusted for these under- and overestimations. We found that between 1990 and 1992 and 2002 and 2006, the adjusted age-specific rates of hip fracture over age 50 years increased 2.76-fold (95% confidence interval [CI], 2.68-2.84) in women and 1.61-fold (95% CI, 1.56-1.66) in men. Over age 70 years, the age-specific rates increased 3.37-fold (95% CI, 3.28-3.47) in women and 2.01-fold (95% CI, 1.95-2.07) in men. From 2002 to 2006, the rates over age 50 years increased 58% in women and 49% in men. We conclude that the rate of hip fracture has been rising very rapidly in Beijing, China. Therefore, the burden of hip fractures may be shifting rapidly from the West to urbanizing areas of the East.
在中国北京，髋部骨折的特定年龄发生率在大多数西方国家都呈下降趋势，但有少数研究表明，在亚洲一些正在经历城市化的地区，这一比率可能在上升。我们之前进行了一项基于人群的研究，对 1990 年至 1992 年北京的髋部骨折发病率进行了研究，其中包括对髋部骨折病例进行了验证。我们使用类似的方法对病例进行验证，估计了 2002 年至 2006 年北京的特定年龄髋部骨折发生率。具体来说，我们获得了向北京市卫生局报告的髋部骨折住院数据。为了确认诊断、北京居民身份，并发现记录中遗漏的病例，我们在北京市随机抽取的医院的病历中逐一核对了公共卫生记录中的病例。根据这些低估和高估情况，对公共卫生数据中的发生率进行了调整。我们发现，1990 年至 1992 年和 2002 年至 2006 年之间，50 岁以上女性髋部骨折的特定年龄调整发生率增加了 2.76 倍（95%置信区间[CI]，2.68-2.84），男性增加了 1.61 倍（95% CI，1.56-1.66）。70 岁以上的女性髋部骨折的特定年龄调整发生率增加了 3.37 倍（95% CI，3.28-3.47），男性增加了 2.01 倍（95% CI，1.95-2.07）。从 2002 年到 2006 年，女性髋部骨折的发生率增加了 58%，男性髋部骨折的发生率增加了 49%。我们的结论是，髋部骨折在北京的发生率正在迅速上升。因此，髋部骨折的负担可能正在从西方迅速转移到东方的城市化地区。
