多中心性Castleman病：三例报告。

Multicentric Castleman's disease: Report of three cases.

作者信息

Guazzaroni M, Bocchinfuso F, Vasili E, Lacchè A, Ranalli T, Garipoli A, Di Tosto F, Floris R

机构信息

Department of Diagnostic and Molecular Imaging, Interventional Radiology and Radiation Therapy, Fondazione Policlinico "Tor Vergata," viale Oxford 81, Rome 00133, Italy.

出版信息

Radiol Case Rep. 2018 Dec 13;14(3):328-332. doi: 10.1016/j.radcr.2018.10.005. eCollection 2019 Mar.

DOI:10.1016/j.radcr.2018.10.005

PMID:30581518

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6297056/

Abstract

Castleman's disease is an uncommon benign B-cell lymphoproliferative disorder. According to lymph nodes distribution, there are two distinct subtypes of disease: unicentric and multicentric. Unicentric Castleman's disease is more common, localized to one site, and locally treated. On the contrary, multicentric form is a rare systemic disease characterized by diffuse lymphadenopathy and inflammatory symptoms. We report three cases of persons that were initially suspected to have a lymphoma but were later histologically confirmed to have Multicentric Castleman's Disease. In addition, our work aims to investigate the role of fluorodeoxyglucose (FDG) PET/CT in evaluation of this rare condition.

摘要

卡斯特曼病是一种罕见的良性B细胞淋巴增殖性疾病。根据淋巴结分布情况，该病有两种不同的亚型：单中心型和多中心型。单中心型卡斯特曼病更为常见，局限于一个部位，采用局部治疗。相反，多中心型是一种罕见的全身性疾病，其特征为弥漫性淋巴结病和炎症症状。我们报告了三例最初怀疑患有淋巴瘤但后来经组织学确诊为多中心型卡斯特曼病的病例。此外，我们的工作旨在研究氟脱氧葡萄糖（FDG）PET/CT在评估这种罕见疾病中的作用。