胃肠道气体
Gastrointestinal gas.
作者信息
Fardy J, Sullivan S
机构信息
Division of Gastroenterology, University of Western Ontario, London.
出版信息
CMAJ. 1988 Dec 15;139(12):1137-42.
Complaints related to gastrointestinal gas are commonly encountered in clinical practice. Various therapies have been proposed, yet none has appeared to be extremely effective. A review of the literature revealed little hard evidence to support the use of simethicone, pancreatic enzymes, anticholinergic agents or antibiotics. Evidence supporting the use of prokinetic agents has been the strongest, and there may be a pathophysiologic basis for the use of these agents if the complaints are related to abnormal intestinal motility. The use of activated charcoal for adsorbing intestinal gas has been effective in healthy subjects but has not been properly investigated in patients with gas complaints. Dietary modification may be beneficial in certain cases. Additional controlled trials are necessary to clarify the issues in the treatment of this common problem.
在临床实践中，与胃肠道气体相关的主诉很常见。人们提出了各种治疗方法，但似乎都不是极其有效。文献综述显示，几乎没有确凿证据支持使用西甲硅油、胰酶、抗胆碱能药物或抗生素。支持使用促动力药物的证据最为充分，如果主诉与肠道运动异常有关，那么使用这些药物可能有病理生理学依据。活性炭吸附肠道气体在健康受试者中已证明有效，但在有气体相关主诉的患者中尚未得到充分研究。在某些情况下，饮食调整可能有益。需要更多的对照试验来阐明这个常见问题的治疗要点。
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