Boiko R V, Bilko D I, Russu I Z, Bilko N M
National University of Kyiv-Mohyla Academy, G. Skovorody Str. 2, Kyiv 04070.
Probl Radiac Med Radiobiol. 2018 Dec;23:229-234. doi: 10.33145/2304-8336-2018-23-229-234.
to determine the quantitative characteristics of population functioning of mice bone marrow colony-forming units during seven days of acute fractionated irradiation.
Assigned task is solved by means of described in works R. V. Boiko et al. (2015, 2016) math-ematical model of alterations in the number of bone marrow colony-forming units using the experimental results ofwork W.Chu-Tse, L. G.Lajtha (1975). Mathematical model is developed basing on the new hematopoiesis scheme,which was introduced by I. Chertkov(1984, 1991).
By applying original mathematical model of hematopoiesis scheme using results concerning the change innumber of bone marrow colony-forming units of mice femur we determined quantitative characteristics of theirfunctioning during seven days of fractionated irradiation under daily acute γ-radiation in the dose of 0.7 Gy.
Mathematical model is introduced, which describes changes in the relative number of colony-formingunits in mice bone marrow in the process of their acute fractionated irradiation.
确定小鼠骨髓集落形成单位在急性分次照射7天期间的群体功能定量特征。
通过R. V. 博伊科等人（2015年、2016年）著作中描述的骨髓集落形成单位数量变化的数学模型，利用W. 朱 - 泽、L. G. 拉伊塔（1975年）的实验结果来解决指定任务。该数学模型是基于I. 切尔特科夫（1984年、1991年）提出的新造血方案开发的。
通过应用基于造血方案的原始数学模型，并利用小鼠股骨骨髓集落形成单位数量变化的结果，我们确定了在每日0.7 Gy急性γ射线照射下分次照射7天期间它们的功能定量特征。
引入了数学模型，该模型描述了小鼠骨髓中集落形成单位在急性分次照射过程中的相对数量变化。
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