Woźniakowski Grzegorz, Frant Maciej, Mamczur Andrzej
Department of Swine Diseases, National Veterinary Research Institute, 24-100 Pulawy, Poland.
Avi-Vet Service, Mamczur J., Szeptycki S.J., 62-080 Tarnowo Podgórne, Poland.
J Vet Res. 2018 Dec 10;62(3):257-260. doi: 10.2478/jvetres-2018-0036. eCollection 2018 Sep.
Avian reticuloendotheliosis (RE) represents an important immunosuppressive disease of poultry. The occurrence of RE in both chickens and turkeys has an immunosuppressive effect and may lead to vaccination failures. Avian reticuloendotheliosis virus (REV) is widely distributed in different kinds of birds, causing subclinical infections. Another important issue adhering to this disease is contamination of vaccines against fowl pox (FP) and Marek's disease (MD) with REV. The capability of REV to integrate into the genome of other larger DNA viruses complicates its diagnosis and prevention. There are no efficient vaccines against RE nor treatment, which also complicates how to limit its impact on poultry farming. This paper reviews the current state of knowledge of this important immunosuppressive agent of poultry emphasising the importance of this problem in terms of diagnosis of RE.
禽网状内皮组织增殖病（RE）是家禽的一种重要免疫抑制性疾病。鸡和火鸡发生RE均具有免疫抑制作用，可能导致疫苗接种失败。禽网状内皮组织增殖病病毒（REV）广泛分布于不同种类的鸟类中，引起亚临床感染。与这种疾病相关的另一个重要问题是鸡痘（FP）和马立克氏病（MD）疫苗被REV污染。REV整合到其他较大DNA病毒基因组中的能力使其诊断和预防变得复杂。目前尚无针对RE的有效疫苗或治疗方法，这也使得如何限制其对家禽养殖的影响变得复杂。本文综述了关于这种重要的家禽免疫抑制因子的当前知识状态，强调了该问题在RE诊断方面的重要性。
