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伊朗的耳念珠菌真菌病及近期文献回顾。

Candida auris otomycosis in Iran and review of recent literature.

机构信息

Department of Medical Mycology/Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.

出版信息

Mycoses. 2019 Feb;62(2):101-105. doi: 10.1111/myc.12886.

Abstract

Candida auris is a multidrug-resistant yeast emerging in immunocompromised and in otherwise healthy individuals. Due to difficulties in microbiological identification of C. auris because of the lack of available laboratory technology in developing countries, the number of patients affected is most likely underestimated. We report the first case of C. auris otitis which now adds Iran as the fifth country around the Persian Gulf, in addition to Kuwait, Oman, United Arab Emirates and Saudi Arabia. Candida auris is an unknown pathogen in routine laboratories in Iran because most Candida isolates are probably misdiagnosed. Otomycosis seems to be a different clinical presentation of C. auris mainly involving isolates from the East-Asian clade. We compared the mycological and clinical details of the Iranian patient with other cases of otitis reported since the last review of C. auris otomycosis in 2017.

摘要

耳念珠菌是一种在免疫功能低下和健康人群中出现的多药耐药酵母菌。由于发展中国家缺乏可用的实验室技术,导致耳念珠菌的微生物学鉴定存在困难,因此受影响的患者数量很可能被低估。我们报告了首例耳念珠菌性耳炎病例,这使伊朗成为继科威特、阿曼、阿拉伯联合酋长国和沙特阿拉伯之后,波斯湾地区的第五个出现该病例的国家。在伊朗的常规实验室中,耳念珠菌是一种未知病原体,因为大多数念珠菌分离株可能被误诊。耳真菌病似乎是耳念珠菌的一种不同临床表现,主要涉及东亚谱系的分离株。我们将伊朗患者的微生物学和临床细节与 2017 年最后一次审查耳念珠菌性耳炎以来报告的其他耳炎病例进行了比较。

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