Chen Jingjing, Si Youjiao, Zhao Kaikai, Shi Xianglong, Bi Weiqun, Liu Shi-En, Hua Hui
Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong Province, China.
Department of Radiology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, 264100, Shandong Province, China.
BMC Med Imaging. 2018 Dec 27;18(1):56. doi: 10.1186/s12880-018-0299-8.
To explore the value of parameters of multiphase dynamic contrast-enhanced magnetic resonance imaging (MDCE-MRI) in the qualitative diagnosis of hepatic masses.
Eighty patients with hepatic masses were retrospectively analyzed. All the patients underwent MDCE-MRI at 3.0 T MR before treatment. Mean enhancement time (MET), positive enhancement integral (PEI), a maximum slope of increase (MSI), and a maximum slope of decrease (MSD) were measured.
There were significant differences between benign and malignant hepatic masses with respect to MET, PEI, and MSI values. The PEI and MSI values between hemangiomas, hepatocellular carcinomas (HCCs), cholangiocarcinomas, and metastatic tumors had significant differences. The MSD value between metastatic tumors, HCCs, and hemangiomas were significantly different. The area under the curve (AUC) values of the receiver operator characteristic curves for MET, PEI, and MSI were 0.70, 0.72, and 0.80, respectively. The specificity of MET, PEI, and MSI were all 77%, and the sensitivities of MSI was the highest, of which was 82.40%. Logistic regression analysis showed the regression equation to be P = 1/[1 + e], and taking the Youden index maximum points as a diagnostic point was 0.2946.
Some parameters of MDCE-MRI have significant roles in differentiating hepatic masses.
探讨多期动态对比增强磁共振成像（MDCE-MRI）参数在肝脏肿块定性诊断中的价值。
回顾性分析80例肝脏肿块患者。所有患者在治疗前行3.0 T MR的MDCE-MRI检查。测量平均强化时间（MET）、强化阳性积分（PEI）、最大上升斜率（MSI）和最大下降斜率（MSD）。
良性和恶性肝脏肿块在MET值、PEI值和MSI值方面存在显著差异。血管瘤、肝细胞癌（HCC）、胆管癌和转移瘤之间的PEI值和MSI值存在显著差异。转移瘤、HCC和血管瘤之间的MSD值有显著差异。MET、PEI和MSI的受试者操作特征曲线的曲线下面积（AUC）值分别为0.70、0.72和0.80。MET、PEI和MSI的特异性均为77%，MSI的敏感性最高，为82.40%。Logistic回归分析显示回归方程为P = 1/[1 + e]，以约登指数最大值点作为诊断点为0.2946。
MDCE-MRI的一些参数在鉴别肝脏肿块方面具有重要作用。
