定量磁共振成像在肝脏局灶性病变中的应用：弥合研究与临床实践之间的差距。
Quantitative magnetic resonance imaging for focal liver lesions: bridging the gap between research and clinical practice.
机构信息
Service de Radiologie, Hôpital Beaujon, APHP.Nord, Clichy, France.
Section of Radiology - BiND, University Hospital "Paolo Giaccone", Via del Vespro 129, 90127 Palermo, Italy.
出版信息
Br J Radiol. 2021 Jun 1;94(1122):20210220. doi: 10.1259/bjr.20210220. Epub 2021 May 14.
Abstract
Magnetic resonance imaging (MRI) is highly important for the detection, characterization, and follow-up of focal liver lesions. Several quantitative MRI-based methods have been proposed in addition to qualitative imaging interpretation to improve the diagnostic work-up and prognostics in patients with focal liver lesions. This includes DWI with apparent diffusion coefficient measurements, intravoxel incoherent motion, perfusion imaging, MR elastography, and radiomics. Multiple research studies have reported promising results with quantitative MRI methods in various clinical settings. Nevertheless, applications in everyday clinical practice are limited. This review describes the basic principles of quantitative MRI-based techniques and discusses the main current applications and limitations for the assessment of focal liver lesions.
摘要
磁共振成像（MRI）对于检测、描述和随访局灶性肝病变非常重要。除了定性成像解读外，还提出了几种基于 MRI 的定量方法，以改善局灶性肝病变患者的诊断和预后。这些方法包括弥散加权成像及其表观扩散系数测量、体素内不相干运动、灌注成像、磁共振弹性成像和放射组学。多项研究报告了定量 MRI 方法在各种临床环境中的有前景的结果。然而，其在日常临床实践中的应用仍受到限制。本综述描述了基于 MRI 的定量技术的基本原理，并讨论了其在评估局灶性肝病变中的主要当前应用和局限性。
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