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银屑病的流行病学。一项基于人群的研究。

Epidemiology of Psoriasis. A Population-Based Study.

作者信息

Fernández-Armenteros J M, Gómez-Arbonés X, Buti-Solé M, Betriu-Bars A, Sanmartin-Novell V, Ortega-Bravo M, Martínez-Alonso M, Casanova-Seuma J M

机构信息

Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, España; Servicio de Dermatología, Hospital Universitari Arnau de Vilanova, Lleida, España.

Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, España; Universidad de Lleida, Lleida, España.

出版信息

Actas Dermosifiliogr (Engl Ed). 2019 Jun;110(5):385-392. doi: 10.1016/j.ad.2018.10.015. Epub 2018 Dec 23.

DOI:10.1016/j.ad.2018.10.015
PMID:30587329
Abstract

BACKGROUND AND OBJECTIVES

Psoriasis is a chronic immunoinflammatory skin disease very frequent in the western world. Several authors have tried to calculate its prevalence in different regions, although most of them obtained the data from surveys and there are few publications from Mediterranean areas. The objective of our study was to analyze the prevalence and severity of psoriasis in Lleida (a northeastern region in Spain), identify age and sex specific differences and compare our results with other European series.

MATERIALS AND METHODS

A joint database of primary care medicine and the dermatology department was obtained from the entire province of Lleida with epidemiological data and psoriasis diagnosis and treatment codification.

RESULTS

A corrected database was obtained with 398,701 individuals and 6,868 of them (1.72%) were coded with the diagnosis of psoriasis. The prevalence was significantly higher in men than in women (1.88% vs 1.56%, OR=1.21, 95% CI: 1.15-1.27). The highest prevalence of psoriasis was found in the 61-70 years group (2.90%) and psoriasis in population under 18 years of age was 0.30%. In our sample, 7.27% of the patients were classified as moderate-severe psoriasis (499/6,868).

CONCLUSION

This study reports the prevalence and severity of psoriasis in a large Mediterranean region sample, obtaining the information through a electronic database. This study reveals a lower prevalence of psoriasis compared to other European countries, and the proportion of severe psoriasis (based on treatment criteria) is lower than in other studies. We emphasize that these differences could probably due to genetic background, life style and diet.

摘要

背景与目的

银屑病是一种慢性免疫炎症性皮肤病,在西方世界非常常见。几位作者试图计算其在不同地区的患病率,尽管他们大多通过调查获取数据,而来自地中海地区的相关出版物较少。我们研究的目的是分析西班牙东北部莱里达市银屑病的患病率和严重程度,确定年龄和性别特异性差异,并将我们的结果与其他欧洲系列研究进行比较。

材料与方法

通过莱里达省的基层医疗和皮肤科联合数据库获取流行病学数据以及银屑病诊断和治疗编码。

结果

获得了一个经过校正的数据库,包含398,701人,其中6,868人(1.72%)被编码为银屑病诊断。男性患病率显著高于女性(1.88%对1.56%,OR = 1.21,95% CI:1.15 - 1.27)。银屑病患病率最高的是61 - 70岁年龄组(2.90%),18岁以下人群的银屑病患病率为0.30%。在我们的样本中,7.27%的患者被归类为中度至重度银屑病(499/6,868)。

结论

本研究通过电子数据库获取信息,报告了地中海大区域样本中银屑病的患病率和严重程度。与其他欧洲国家相比,本研究显示银屑病患病率较低,且(基于治疗标准的)重度银屑病比例低于其他研究。我们强调这些差异可能归因于遗传背景、生活方式和饮食。

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