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具有年龄结构接触率的流行病模型的阈值和稳定性结果。

Threshold and stability results for an epidemic model with an age-structured meeting rate.

作者信息

Greenhalgh D

机构信息

Department of Mathematics, University of Strathclyde, Glasgow, UK.

出版信息

IMA J Math Appl Med Biol. 1988;5(2):81-100. doi: 10.1093/imammb/5.2.81.

Abstract

This paper examines threshold and stability results for simple mathematical models for the transmission of infectious diseases with permanent natural immunity. Examples of such diseases are measles, chicken-pox, hepatitis, and mumps. An important feature of this work is the introduction of an age structure into the population amongst whom the disease is spreading and, in particular, the realization of the fact that the contact rate itself may depend on age. Equilibrium and stability analyses are performed on these models. These results are in part directed towards establishing conditions sufficient for the existence of a nonzero equilibrium disease level to be possible. Conjectures about the existence of a nonzero solution to a set of partial integrodifferential equations are examined. These conditions determine the circumstances under which the disease will persist. Particular emphasis is devoted to the case where the meeting rate depends on age.

摘要

本文研究了具有永久自然免疫力的传染病传播简单数学模型的阈值和稳定性结果。这类疾病的例子有麻疹、水痘、肝炎和腮腺炎。这项工作的一个重要特征是在疾病传播的人群中引入了年龄结构,特别是认识到接触率本身可能取决于年龄这一事实。对这些模型进行了平衡和稳定性分析。这些结果部分旨在确定足以使非零平衡疾病水平存在成为可能的条件。研究了关于一组偏积分微分方程非零解存在性的猜想。这些条件决定了疾病持续存在的情况。特别强调了接触率取决于年龄的情况。

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