Ibrakhim R M, Averyanov D A, Schegolev A V, Makarenko E P
Voen Med Zh. 2016 Jul;337(7):11-17.
The aim of the study was to compare the effect of sevoflurane and desflurane on the rate of patient awakening from anaesthesia, recovery of orientation, memory and concentration, and the incidence of side effects after elective surgery on the brain. The study included 42 patients, divided into two equal groups. In the first as the main anaesthetic used sevoflurane, in the second - desflurane. Wake-up time, and extubation of recovery of consciousness after desfluranom was less than when using sevoflurane as a anesthetic by 185, 301 and 296, respectively. Time needed for orientation, memory and concentration recovery varied in 15 and 30 minutes (in the desflurane group were faster) after waking up with full recovery in the preoperative level after 2 hours. Using desflurane was not accompanied by deterioration in the operations environment and does not lead to an increase in the number of adverse postoperative phenomena.
该研究的目的是比较七氟烷和地氟烷对择期脑手术后患者麻醉苏醒速度、定向力、记忆力和注意力恢复以及副作用发生率的影响。该研究纳入了42例患者，分为两组，每组人数相等。第一组主要使用七氟烷作为麻醉剂，第二组使用地氟烷。地氟烷麻醉后的苏醒时间和意识恢复后拔管时间分别比使用七氟烷麻醉时短185、301和296秒。苏醒后恢复定向力、记忆力和注意力所需的时间在15至30分钟之间（地氟烷组恢复得更快），2小时后完全恢复到术前水平。使用地氟烷不会使手术环境恶化，也不会导致术后不良现象数量增加。
