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房间隔缺损手术封堵与经导管封堵后的短期结局:一项来自伊朗的研究。

Short-term outcomes after surgical versus trans catheter closure of atrial septal defects; a study from Iran.

作者信息

Askari Behnam, Soraya Hamid, Ayremlu Nasim, Golmohammadi Mitra

机构信息

Department of Cardiovascular Surgery, Seyyed-al-Shohada Heart Center, Urmia University of Medical Sciences, Urmia, Iran.

Department of Pharmacology, Faculty of Pharmacy, Urmia University of Medical Sciences, Urmia, Iran.

出版信息

Egypt Heart J. 2018 Dec;70(4):249-253. doi: 10.1016/j.ehj.2018.09.003. Epub 2018 Sep 17.

Abstract

OBJECTIVES

Atrial Septal Defect (ASD) accounts for 10% of congenital cardiac defects. The purpose of this retrospective study was to compare the short-term outcomes of surgical versus trans catheter closure of secundum atrial septal defect.

METHODS

This is a single-center retrospective cohort study in patients who had surgical or trans catheter ASD closure. ASD closure outcomes such as hospital cost, length of hospital and ICU stay, residual ASDs, complications, readmission, hospital and three month mortality were recorded and compared.

RESULTS

Between March 2010 and March 2016, total of 102 secundum ASD patients were treated in our center (71 patients surgical ASD closure and 31 patients trans catheter ASD closure). About 13.9% of patients (5/36) in the device group had failed procedural attempt for various reasons and these patients underwent surgery closure. Complete closure was observed in 26 of 31 patients (83.9%) in the device group and in 70 of 71 patients in the surgery group (98.6%). The mean length of hospital stay was 5.56 days for surgical group and 2.06 days for device group. The procedure cost for surgery was found to be 5.7% lower than trans catheter closure (patient payment). The complication rates were 18.3% for surgical group and 25.8% for the device group. Readmission after discharge was more common in surgery group (11.2 vs 6.4%). Hospital and three months mortality in both groups were zero.

CONCLUSIONS

Both trans catheter and surgical procedure are good methods of successful ASD closure. Considering that the surgical group patients were higher risk patients, mean total hospital cost of patient's procedures were significantly higher in device closure group, failed intervention rate and residual ASD were more common in device group and complications of device group were more serious; thus, appropriate patient selection is an important factor for successful device closure.

摘要

目的

房间隔缺损(ASD)占先天性心脏缺陷的10%。本回顾性研究的目的是比较继发孔型房间隔缺损外科手术闭合与经导管闭合的短期疗效。

方法

这是一项针对接受外科手术或经导管ASD闭合治疗患者的单中心回顾性队列研究。记录并比较ASD闭合的相关结果,如住院费用、住院时间和重症监护病房(ICU)停留时间、残余ASD、并发症、再入院情况、住院死亡率和三个月死亡率。

结果

2010年3月至2016年3月期间,本中心共治疗了102例继发孔型ASD患者(71例行外科ASD闭合,31例行经导管ASD闭合)。器械组约13.9%的患者(5/36)因各种原因手术尝试失败,这些患者接受了手术闭合。器械组31例患者中有26例(83.9%)实现完全闭合,手术组71例患者中有70例(98.6%)实现完全闭合。外科组的平均住院时间为5.56天,器械组为2.06天。发现手术的费用比经导管闭合(患者支付)低5.7%。外科组的并发症发生率为18.3%,器械组为25.8%。出院后再入院在手术组更为常见(11.2%对6.4%)。两组的住院死亡率和三个月死亡率均为零。

结论

经导管和外科手术都是成功闭合ASD的良好方法。考虑到外科组患者风险更高,器械闭合组患者手术的平均总住院费用显著更高,器械组干预失败率和残余ASD更常见,且器械组并发症更严重;因此,合适的患者选择是器械闭合成功的重要因素。

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