Hocaoğlu-Emre F. Sinem, Sarıbal Devrim, Oğuz Osman
Beykent University School of Health Sciences, Department of Nutrition and Dietetics, İstanbul, Turkey
İstanbul University Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Department of Biophysics, İstanbul, Turkey
J Clin Res Pediatr Endocrinol. 2019 May 28;11(2):181-188. doi: 10.4274/jcrpe.galenos.2018.2018.0272. Epub 2018 Dec 28.
This study aimed to determine the ratio of seasonal vitamin D deficiency and insufficiency in elementary school children aged between 6-9 years old, living in one of the largest metropols of Europe, İstanbul.
Serum 25(OH)D levels of 640 children aged 6-9 years old were scanned retrospectively from the hospital information system records between September 2017-August 2018 period. Vitamin D deficiency was defined as a serum 25(OH)D level less than 12 ng/mL (30 nmol/L) and insufficiency as levels between 12 and 20 ng/mL (30-50 nmol/L).
Serum 25(OH)D levels ranged from 3.90 to 64.60 ng/mL, the median value was 25.95 ng/mL for all subjects. Of all the primary school children, 485 (75.78%) had adequate levels of 25(OH)D. Vitamin D deficiency was observed in 36 of children (5.62%), whereas insufficient levels of 25(OH)D were found in 119 children (18.60%). The ratio of vitamin D insufficiency and deficiency together was highest in spring (31.87%) and lowest in summer (13.12%).
Vitamin D deficiency is a widely observed and preventable public health problem among children of different ages. It is necessary to increase the awareness among health professionals, and providing 25(OH)D supplements will yield generations with healthy bone structure and well growth.
本研究旨在确定居住在欧洲最大的大都市之一伊斯坦布尔的6至9岁小学生季节性维生素D缺乏和不足的比例。
回顾性分析2017年9月至2018年8月期间医院信息系统记录的640名6至9岁儿童的血清25(OH)D水平。维生素D缺乏定义为血清25(OH)D水平低于12 ng/mL(30 nmol/L),不足定义为水平在12至20 ng/mL(30 - 50 nmol/L)之间。
血清25(OH)D水平范围为3.90至64.60 ng/mL,所有受试者的中位数为25.95 ng/mL。在所有小学生中,485名(75.78%)25(OH)D水平充足。36名儿童(5.62%)存在维生素D缺乏,而119名儿童(18.60%)25(OH)D水平不足。维生素D不足和缺乏的比例总和在春季最高(31.87%),夏季最低(13.12%)。
维生素D缺乏是不同年龄段儿童中广泛存在且可预防的公共卫生问题。有必要提高卫生专业人员的认识,提供25(OH)D补充剂将培养出具有健康骨骼结构和良好生长发育的一代。