Sanmarco M, Heim M, Bernard D, Simonin R
Laboratoire d'Immunopathologie, Faculté de Médecine de Marseille, France.
Pathol Biol (Paris). 1988 Sep;36(7):867-70.
Thyroid autoantibodies have been found in 28 to 38 per cent of Sjögren's syndrome cases. In this study, we inversely investigated, the presence of Sjögren's syndrome antibodies in autoimmune thyroid diseases, ie rheumatoid factors, antinuclear soluble antigens SSB/La and SSA/RO, anti-salivary ducts. Results show no increased incidence of these antibodies in autoimmune thyroid diseases as compared to those of control subjects. So, no significant immune abnormality association is found between these two autoimmune disorders.
在28%至38%的干燥综合征病例中发现了甲状腺自身抗体。在本研究中,我们反向调查了自身免疫性甲状腺疾病中干燥综合征抗体的存在情况,即类风湿因子、抗核可溶性抗原SSB/La和SSA/RO、抗唾液腺导管。结果显示,与对照组相比,这些抗体在自身免疫性甲状腺疾病中的发生率并未增加。因此,未发现这两种自身免疫性疾病之间存在显著的免疫异常关联。