Scherbaum W A, Youinou P Y, Le Goff P, Bottazzo G F
Clin Exp Immunol. 1984 Mar;55(3):516-8.
Anti-perinuclear factors (APF), IgM-, IgG- and IgA-rheumatoid factors have been detected in six, five, one and three out of 20 patients with primary myxoedema, respectively. We were unable to find APF in 22 patients with Hashimoto's thyroiditis nor in 20 patients with Graves' thyrotoxicosis. APF appears to be a marker for non-organ specific autoimmune diseases.
在20例原发性黏液性水肿患者中,分别有6例、5例、1例和3例检测到抗核周因子(APF)、IgM类风湿因子、IgG类风湿因子和IgA类风湿因子。我们在22例桥本甲状腺炎患者和20例格雷夫斯甲状腺毒症患者中均未发现APF。APF似乎是非器官特异性自身免疫性疾病的一个标志物。