Long Shengrong, Li Mingdong, Ou Shaowu, Li Guangyu
Department of Neurosurgery, First Affiliated Hospital of China Medical University, Shenyang, China.
Medicine (Baltimore). 2018 Dec;97(52):e13900. doi: 10.1097/MD.0000000000013900.
To study the effect of marital status on survival outcome in people diagnosed with glioma, not otherwise specified using the Surveillance, Epidemiology, and End Results (SEER) database.We chose patients diagnosed with glioma between 2000 and 2014 from the SEER database and recorded their disease-related data. We then analyzed overall 5-year cause-specific survival with respect to different marital statuses. There were 617 patients (262 women and 355 men). Of these, 54.0% (n = 333), 24.6% (n = 152), 8.6% (n = 53), and 12.8% (n = 79) were married, single, divorced (or separated), and widowed, respectively. The 5-year cause-specific survival was 39.30%, 64.50%, 60.40%, and 10.10% in the married, single, divorce (or separated), and widowed groups, respectively. The widowed group had substantially higher risk of glioma-related death than did the married group (hazard ratio 1.77, 95% confidence interval 1.337-2.344, P < .001). Being widowed provided higher risk of glioma mortality compared than did marital statuses. Widowed people should be given more support and psychological intervention by society.
利用监测、流行病学和最终结果（SEER）数据库，研究婚姻状况对未另作说明的胶质瘤患者生存结局的影响。我们从SEER数据库中选取了2000年至2014年间被诊断为胶质瘤的患者，并记录他们的疾病相关数据。然后，我们分析了不同婚姻状况下的总体5年特定病因生存率。共有617例患者（262例女性和355例男性）。其中，已婚、单身、离异（或分居）和丧偶的患者分别占54.0%（n = 333）、24.6%（n = 152）、8.6%（n = 53）和12.8%（n = 79）。已婚、单身、离异（或分居）和丧偶组的5年特定病因生存率分别为39.30%、64.50%、60.40%和10.10%。丧偶组与已婚组相比，胶质瘤相关死亡风险显著更高（风险比1.77，95%置信区间为(1.337 - 2.344)，P < 0.001）。与其他婚姻状况相比，丧偶导致胶质瘤死亡的风险更高。社会应给予丧偶者更多支持和心理干预。
