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关于通过全身和局部应用对肿瘤进行成像的超亮荧光醋酸纤维素纳米颗粒的数据。

Data on ultrabright fluorescent cellulose acetate nanoparticles for imaging tumors through systemic and topical applications.

作者信息

Peng Berney, Almeqdadi Mohammad, Laroche Fabrice, Palantavida Shajesh, Dokukin Maxim, Roper Jatin, Yilmaz Omer H, Feng Hui, Sokolov Igor

机构信息

Department of Biomedical Engineering, Tufts University, Medford, MA, USA.

Department of Medicine, St. Elizabeth׳s Medical Center, Boston, MA, USA.

出版信息

Data Brief. 2018 Dec 18;22:383-391. doi: 10.1016/j.dib.2018.12.030. eCollection 2019 Feb.

DOI:10.1016/j.dib.2018.12.030
PMID:30596135
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6307339/
Abstract

Characterization data of fluorescent nanoparticles made of cellulose acetate (CA-dots) are shown. The data in this article accompanies the research article "" [1]. The measurements and calculation of brightness of individual CA-dots are presented. The description of conjugation procedure Pluronic F127-Folic Acid copolymer and folic acid is shown. Identification of composition of CA dots using Raman and absorbance spectroscopy is demonstrated. The methods for image analysis of efficiency of CA-dot targeting of epithelial tumors xenografted in zebrafish is presented.

摘要

展示了由醋酸纤维素制成的荧光纳米颗粒(CA 点)的表征数据。本文中的数据与研究论文“”[1] 相关。介绍了单个 CA 点亮度的测量和计算。展示了普朗尼克 F127 - 叶酸共聚物与叶酸的共轭过程描述。证明了使用拉曼光谱和吸收光谱对 CA 点成分的鉴定。介绍了对斑马鱼体内移植的上皮肿瘤中 CA 点靶向效率进行图像分析的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/5053a87098b4/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/f92d590a6324/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/6346f315f913/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/3eb145255c5f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/1c6562d231fa/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/036a0d01a093/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/82e8648aca7b/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/040ee704ddd2/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/5053a87098b4/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/f92d590a6324/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/6346f315f913/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/3eb145255c5f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/1c6562d231fa/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/036a0d01a093/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/82e8648aca7b/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/040ee704ddd2/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5963/6307339/5053a87098b4/gr8.jpg

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本文引用的文献

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J Mater Chem B. 2014 May 28;2(20):3107-3114. doi: 10.1039/c4tb00287c. Epub 2014 Apr 14.
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Mater Today (Kidlington). 2019 Mar;23:16-25. doi: 10.1016/j.mattod.2018.11.001. Epub 2018 Dec 23.
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