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尼日利亚奥约州结核病发病模式及其相关因素的建模

MODELLING THE MORBIDITY PATTERN OF TUBERCULOSIS AND ITS ASSOCIATED FACTORS IN OYO STATE, NIGERIA.

作者信息

Bidemi Yusuf Oyindamola, Ayobami Adepoju-Olajuwon Fatimah, Olamiposi Owoeye Deborah, Abbas Gbolahan

机构信息

Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan. Nigeria.

Evaluation and Operation Research Department, Association for Reproductive and Family Health, (ARFH), Agodi, Ibadan. Nigeria.

出版信息

Afr J Infect Dis. 2018 Dec 12;13(1):11-23. doi: 10.21010/ajid.v13i1.2. eCollection 2019.

Abstract

BACKGROUND

With the advent of HIV, the risk of Tuberculosis (TB) has increased. The trend in the number of cases of TB in Oyo State over the past five years has not been documented. Hence, this study reviewed the number of cases of TB and determined some of its associated factors.

MATERIALS AND METHODS

A retrospective analysis was conducted on TB surveillance data reported between January 1 2011 and December 31 2014. Data were obtained from the integrated disease surveillance and response (IDSR) of Oyo State Ministry of Health, Nigeria. Number of TB cases, age, local government areas (LGA), month and year of reporting was extracted. Data were analyzed using descriptive statistics, negative binomial and the Poisson regression models. Model fit was assessed using the AIC and the -2LogL.

RESULTS

The incidence of TB was highest in 2013 (23 per 10000 population) in Ibarapa East LGA. The risk of Tuberculosis was 62.8% higher in 2014 (IRR = 1.628; 95%CI = 1.281, 2.068) and also 17% higher in 2012 (IRR = 1.170; 95%CI = 1.010, 1.356). Also, the risk of TB was highest in Ibarapa East LGA (IRR = 2.576; 95%CI = 1.945, 3.412) and lowest in Ogbomoso South LGA (IRR = 0.229; 95%CI = 0.069, 0.764). Adolescents and adults also had higher risk of TB compared to children.

CONCLUSION

The frequency of Tuberculosis declined overtime and older adults had a higher risk. The low frequency of TB in the state may be an indication and good evidence of concerted control measures. Efforts should be put in place to further bring down the number of cases especially in the identified hotspots.

摘要

背景

随着艾滋病病毒的出现,结核病(TB)的风险增加。过去五年奥约州结核病病例数的趋势尚未有文献记载。因此,本研究回顾了结核病病例数并确定了一些相关因素。

材料与方法

对2011年1月1日至2014年12月31日期间报告的结核病监测数据进行回顾性分析。数据来自尼日利亚奥约州卫生部的综合疾病监测与应对(IDSR)。提取结核病病例数、年龄、地方政府区域(LGA)、报告月份和年份。使用描述性统计、负二项式和泊松回归模型对数据进行分析。使用AIC和-2LogL评估模型拟合情况。

结果

2013年伊巴拉帕东地方政府区域的结核病发病率最高(每10000人口23例)。2014年结核病风险高出62.8%(发病率比[IRR]=1.628;95%置信区间[CI]=1.281,2.068),2012年也高出17%(IRR=1.170;95%CI=1.010,1.356)。此外,伊巴拉帕东地方政府区域的结核病风险最高(IRR=2.576;95%CI=1.945,3.412),奥戈莫索南地方政府区域最低(IRR=0.229;95%CI=0.069,0.764)。与儿童相比,青少年和成年人患结核病的风险也更高。

结论

结核病发病率随时间下降,老年人风险更高。该州结核病发病率较低可能表明采取了协调一致的控制措施并提供了有力证据。应进一步努力降低病例数,特别是在已确定的热点地区。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8288/6305077/2940b870beb4/AJID-13-11-g003.jpg

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