Blankenhorn D H, Chin H P, Conover D J, Nessim S A
Department of Medicine, University of Southern California, School of Medicine, Los Angeles 90033.
Ultrasound Med Biol. 1988;14(7):583-7. doi: 10.1016/0301-5629(88)90125-1.
B-mode ultrasound imaging was used to compare pulsation in moderately advanced, non-calcific, common carotid atherosclerotic lesions with adjacent carotid artery walls where no lesions were visible. Subjects were 13 men with proven coronary atherosclerosis. Average age was 54 years and subjects did not have cerebral symptoms or carotid bruits. Ep, the pressure-strain modulus, was estimated using brachial artery blood pressures recorded on the same clinic visit. Ep values in lesion areas were significantly greater than in nonlesion areas. Two extremely high Ep lesion values were found which could not be explained on the basis of focal calcification as determined by ultrasonic or angiographic images. Study of lesion pulsation by ultrasound imaging is proposed as a new noninvasive procedure for characterizing human carotid atherosclerosis.
采用B型超声成像技术，对中度进展性、非钙化性颈总动脉粥样硬化病变部位与未见病变的相邻颈动脉壁的搏动情况进行比较。研究对象为13名经证实患有冠状动脉粥样硬化的男性。平均年龄为54岁，研究对象无脑部症状或颈动脉杂音。通过在同一次门诊就诊时记录的肱动脉血压来估算压力应变模量Ep。病变区域的Ep值显著高于非病变区域。发现了两个极高的Ep病变值，这无法用超声或血管造影图像所确定的局灶性钙化来解释。建议将超声成像对病变搏动的研究作为一种用于描述人类颈动脉粥样硬化特征的新的非侵入性方法。
