Krickeberg H
Universitäts-Hautklinik Köln.
Z Hautkr. 1988 Sep 15;63(9):773-5.
A 45-year-old patient developed squamous cell carcinoma 4 years after renal transplantation and immunosuppressive therapy with azathioprine and fluocortolone. During the following 3 years, the patient developed on sun-exposed skin several premalignant hyperkeratoses, Bowen's carcinoma, basal cell carcinoma, as well as squamous cell carcinoma and carcinoma of the eccrine sweat glands, both showing the clinical picture of keratoacanthoma.
一名45岁患者在肾移植及使用硫唑嘌呤和氟可的松进行免疫抑制治疗4年后发生了鳞状细胞癌。在接下来的3年里,该患者在暴露于阳光的皮肤上出现了多处癌前角化过度、鲍温病、基底细胞癌,以及鳞状细胞癌和小汗腺癌,二者均表现为角化棘皮瘤的临床症状。