Tangiisuran Balamurugan, Jiva Maryam, Ariff Adilah Mohamed, Abdul Rani Noor Afiza, Misnan Asdariah, Rashid Sazaroni Md, Majid Mohamed Isa Abdul, Dawson Andrew H
National Poison Centre, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.
School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.
BMJ Open. 2018 Dec 31;8(12):e024162. doi: 10.1136/bmjopen-2018-024162.
Accidental or intentional poisoning is a public health concern requiring intervention. The current study designs to evaluate the types of poisoning exposure calls received by the Malaysia National Poison Centre (NPC) over a 10-year period.
The poisoning enquiries database (2006-2015) from the Malaysia NPC was used for the analysis.
The NPC records all telephone calls that it manages using a validated and standardised form. Demographics and types of the poisoning exposure calls were extracted and descriptive analysis was applied.
The primary outcome of this study is to evaluate NPC data for trends in the poisoning exposure calls based on the types and modes of poisoning over a 10-year period. The secondary outcome is to evaluate the characteristics of human exposure cases based on the calls received by the NPC.
There was a notable increase in the number of poisoning exposure calls noticed during the 10-year period but dropped significantly in 2012. The highest number of poisoning exposure calls came from Selangor (21.0%), Perak (18.0%) and Negeri Sembilan (9.8%). More than half of the exposure was intentional (53.8%) involving more women (50.3%) as compared with men (41.9%), and in the 20-29 years age group category (33.5%). Exposure mostly occurred at home (96%) through the ingestion route (94.1%). Pharmaceutical products (40.5%), pesticides (31.7%) and household products (20.1%) were the common agents implicated for intentional exposure.
There is an increasing trend in enquiries on poisoning exposure calls made to the NPC. Most of the intentional poisoning exposures occurred among younger women and involved pharmaceuticals, pesticides or household products. Poisoning safety education and other interventions are needed to curb poisoning incidents.
意外或故意中毒是一个需要干预的公共卫生问题。本研究旨在评估马来西亚国家中毒中心(NPC)在10年期间接到的中毒暴露电话的类型。
分析使用了马来西亚NPC的中毒咨询数据库(2006 - 2015年)。
NPC使用经过验证的标准化表格记录所有处理的电话。提取中毒暴露电话的人口统计学信息和类型,并进行描述性分析。
本研究的主要结果是根据中毒类型和方式评估NPC数据中10年期间中毒暴露电话的趋势。次要结果是根据NPC接到的电话评估人类暴露病例的特征。
在这10年期间,中毒暴露电话数量显著增加,但在2012年大幅下降。中毒暴露电话数量最多的来自雪兰莪州(21.0%)、霹雳州(18.0%)和森美兰州(9.8%)。超过一半的暴露是故意的(53.8%),涉及的女性(50.3%)多于男性(41.9%),且多为20 - 29岁年龄组(33.5%)。暴露大多发生在家中(96%),通过摄入途径(94.1%)。药品(40.5%)、农药(31.7%)和家用产品(20.1%)是故意暴露的常见媒介。
向NPC咨询中毒暴露电话的数量呈上升趋势。大多数故意中毒暴露发生在年轻女性中,涉及药品、农药或家用产品。需要开展中毒安全教育和其他干预措施来遏制中毒事件。