Student at Faculty of Medicine, Tanta University, Tanta, Egypt.
Forensic Medicine and Clinical Toxicology Department Faculty of Medicine, Tanta University, Tanta, Egypt.
BMC Pharmacol Toxicol. 2023 Feb 3;24(1):6. doi: 10.1186/s40360-023-00650-5.
Poisoning is a major health problem especially in developing countries and leads to high morbidity and mortality.
To identify the profile of acute poisoning in the Toxicology Unit at Tanta University Hospital, Egypt (2017-2021).
A cross-sectional study using data extracted from medical records from beginning of January 2017 to end of December 2021. Data including demographic data, Glasgow coma scale, type of poisons, manner of poisoning, time of admission and discharge and state at discharge.
This study included 9713 cases. Rodenticides represented the most frequent cause of poisoning among both males (30%) and females (27%). Pharmaceutical drugs, CNS abused pharmaceutical drugs, and chemicals represent the most common categories (24%, 22%, and 21%, respectively) among children (up to 12 years). Rodenticides and pharmaceutical drugs represent the highest categories among other age groups. Evening admissions represented 52% of cases. Glasgow coma scale was 15 among 86.3% of cases. Intentional poisoning was more common than accidental poisoning (58.6% and 34.7%, respectively). One half (52.2%) of the admitted cases were discharged within 24 hours of admission and 44.4% of them were discharged after 48-72 hours. Family request was the main reason of discharge of cases (70.3%), 15.7% were improved, 4% died. Mortality by rodenticide was 12.5%.
Rodenticides, pharmaceutical and CNS abused pharmaceutical drugs were the most common categories of poisoning. Intentional poisoning was more common than accidental poisoning. Rodenticides were responsible for most deaths.
中毒是一个重大的健康问题，尤其在发展中国家，导致高发病率和死亡率。
确定埃及坦塔大学医院毒理学部门（2017-2021 年）急性中毒的特征。
采用回顾性研究，使用 2017 年 1 月初至 2021 年 12 月底从病历中提取的数据。数据包括人口统计学数据、格拉斯哥昏迷评分、毒物类型、中毒方式、入院和出院时间以及出院时的状态。
本研究共纳入 9713 例患者。杀鼠剂是男性（30%）和女性（27%）中毒的最常见原因。儿科（12 岁以下）最常见的中毒物类别为药物、中枢神经系统滥用药物和化学品（分别占 24%、22%和 21%）。其他年龄组中毒物中杀鼠剂和药物的比例最高。傍晚入院的病例占 52%。格拉斯哥昏迷评分为 15 的病例占 86.3%。故意中毒比意外中毒更常见（分别为 58.6%和 34.7%）。一半（52.2%）入院病例在 24 小时内出院，其中 44.4%在 48-72 小时后出院。家属要求是出院的主要原因（70.3%），15.7%的病例病情改善，4%死亡。因杀鼠剂中毒死亡的比例为 12.5%。
杀鼠剂、药物和中枢神经系统滥用药物是最常见的中毒物类别。故意中毒比意外中毒更常见。杀鼠剂是导致大多数死亡的主要原因。
