Academic Team of Musculoskeletal Surgery, University Hospitals of Leicester, Gwendolen Road, Leicester LE5 4PW, UK.
Nuffield Orthopaedic Centre, Windmill road, Oxford OX3 7HE, UK.
Bone. 2019 Apr;121:1-8. doi: 10.1016/j.bone.2018.12.018. Epub 2018 Dec 29.
Social deprivation has been shown to be associated with increased incidence of many types of fracture but the causes for this have not been established. The aim of this study was to establish if distal radius fracture was associated with deprivation and investigate reasons for this.
Data was reviewed of 4463 adult patients who attended our Emergency Department over a four year period. The Index of Multiple Deprivation was used to measure deprivation for each patient. Modelling techniques were used to investigate the relationship between fracture rate and deprivation, gender, ethnicity and age.
Distal radius fracture rate was higher for patients in more deprived quintiles. Mean age in the most deprived two quintiles was 54.4 years compared to 60.1 years in the least deprived three quintiles. Modelling showed important differences between ethnic groups. Deprivation was an independent risk factor for distal radius fracture only in white patients. Deprived white women had a lower second metacarpal cortical index than women of other ethnicities suggesting increased bone fragility. Being male is a risk factor for fracture when deprivation, ethnicity and age are taken into account. Incidence rate ratio of the least deprived quintile compared to the most deprived was 0.33 (95% CI: 0.30-0.37) for white men and 0.47 (95% CI: 0.44-0.49) for white women.
Effective interventions exist to prevent further fragility fracture and this work allows geographical areas at risk to be identified. Presentation with a distal radius fracture provides an opportunity to implement interventions. In the current economic climate resources are scarce and must be used prudently. Resources should be targeted to those at risk patients from deprived areas and preventative strategies put in place.
社会贫困与多种类型骨折的发生率增加有关,但尚未确定其原因。本研究旨在确定桡骨远端骨折是否与贫困有关,并探讨其原因。
回顾了 4463 名在四年期间到我院急诊科就诊的成年患者的数据。使用多因素剥夺指数来衡量每个患者的贫困程度。采用建模技术调查骨折发生率与贫困程度、性别、种族和年龄之间的关系。
桡骨远端骨折发生率在贫困程度较高的五分位组更高。最贫困的两个五分位组的平均年龄为 54.4 岁,而最不贫困的三个五分位组的平均年龄为 60.1 岁。模型显示了不同种族之间的重要差异。贫困仅在白人患者中是桡骨远端骨折的独立危险因素。贫困白人女性的第二掌骨皮质指数低于其他族裔女性,提示骨脆性增加。在考虑贫困程度、种族和年龄的情况下,男性是骨折的危险因素。与最贫困五分位组相比,最不贫困五分位组白人男性的发病率比为 0.33(95%CI:0.30-0.37),白人女性为 0.47(95%CI:0.44-0.49)。
存在有效的干预措施来预防进一步的脆性骨折,这项工作可以确定处于危险中的地理区域。桡骨远端骨折的出现为实施干预措施提供了机会。在当前的经济环境下,资源稀缺,必须谨慎使用。应将资源针对来自贫困地区的高危患者,并制定预防策略。