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颞枕叶胶质母细胞瘤在一名有长期无先兆偏头痛病史的患者中表现为爱丽丝梦游仙境综合征。

Temporal-occipital glioblastoma presenting with Alice in Wonderland Syndrome in a patient with a long-time history of migraine without aura.

作者信息

Mastria Giulio, Mancini Valentina, Viganò Alessandro, De Sanctis Rita, Letteri Federica, Toscano Massimiliano, Di Piero Vittorio

机构信息

a Department of Human Neurosciences , "Sapienza" University of Rome , Rome , Italy.

b Department of Anatomy, Histology, Forensic Medicine, Orthopaedics , Sapienza University of Rome , Rome , Italy.

出版信息

Neurocase. 2018 Oct-Dec;24(5-6):242-244. doi: 10.1080/13554794.2018.1562079. Epub 2019 Jan 2.

Abstract

Alice in Wonderland Syndrome (AIWS) is a rare perceptual disorder characterized by an erroneous perception of the body or the surrounding space. AIWS may be caused by different pathologies, ranging from infections to migraine. We present the case of a 54-year-old man, with a long-time history of migraine without aura, diagnosed with AIWS due to a glioblastoma located in the left temporal-occipital junction. To date, this is the first case of AIWS caused by glioblastoma. This case suggests that to exclude aura-mimic phenomena, a careful diagnostic workup should always be performed even in patients with a long-time history of migraine.

摘要

爱丽丝梦游仙境综合征(AIWS)是一种罕见的感知障碍,其特征是对身体或周围空间的感知错误。AIWS可能由不同的病理状况引起,从感染到偏头痛不等。我们报告一例54岁男性病例,该患者有长期无先兆偏头痛病史,因位于左颞枕交界处的胶质母细胞瘤而被诊断为AIWS。迄今为止,这是首例由胶质母细胞瘤引起的AIWS病例。该病例表明,为排除类似先兆的现象,即使是有长期偏头痛病史的患者,也应始终进行仔细的诊断检查。

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