Chirchiglia Domenico, Chirchiglia Pasquale, Marotta Rosa
Department of Neurosurgery, University of Catanzaro, Campus Germaneto, Vle Europa, 88100, Catanzaro, Italy.
Childs Nerv Syst. 2019 Aug;35(8):1435-1437. doi: 10.1007/s00381-019-04170-8. Epub 2019 May 2.
In this work, we describe an association of brainstem headache with aura (BHA) and Alice in Wonderland syndrome (AIWS) in a 17-year-old male, suffering from crises of vertigo, weakness, dysarthria, and diplopia, in half-hour duration, followed by diffuse or occipital headache, lasting several hours.
The frequency of the attacks was monthly, and once there was short loss of consciousness. The last episodes were accompanied by symptoms such as deformation of figures and objects, small or large in shape.
Diagnostic examinations were performed, mainly neuroimaging tests such as brain MRI and brain angio-MRI, all resulting normal; and treatment with flunarizine was followed by improvement of both BHA and AIWS symptoms.
There would be a correlation between BHA and AIWS, presumably represented by dysfunction of temporo-parieto-occipital carrefour.
在本研究中，我们描述了一名17岁男性患者，其患有脑干性先兆头痛（BHA）和爱丽丝梦游仙境综合征（AIWS），伴有眩晕、虚弱、构音障碍和复视发作，持续半小时，随后出现弥漫性或枕部头痛，持续数小时。
发作频率为每月一次，曾有一次短暂意识丧失。最近的发作伴有诸如人物和物体形状变形等症状，形状有大有小。
进行了诊断检查，主要是神经影像学检查，如脑部MRI和脑部血管造影MRI，结果均正常；使用氟桂利嗪治疗后，BHA和AIWS症状均有所改善。
BHA与AIWS之间可能存在关联，推测是由颞顶枕交界区功能障碍所致。
