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采用生存时间分析方法对种植体周围炎风险指标的纵向研究。

Longitudinal study on risk indicators for peri-implantitis using survival-time analysis.

机构信息

Osaka University Graduate School of Dentistry, Department of Prosthodontics, Gerodontology and Oral Rehabilitation, Suita, Japan.

Osaka University Graduate School of Dentistry, Department of Prosthodontics, Gerodontology and Oral Rehabilitation, Suita, Japan.

出版信息

J Prosthodont Res. 2019 Apr;63(2):216-220. doi: 10.1016/j.jpor.2018.12.002. Epub 2018 Dec 30.

DOI:10.1016/j.jpor.2018.12.002
PMID:30600176
Abstract

PURPOSE

The purpose of this study was to evaluate the incidence of peri-implantitis and to identify potential associated risk indicators.

METHODS

This longitudinal study included 477 patients treated with 1420 implants. Medical and dental histories were evaluated in all patients. The location, size, connection type, surgical protocol, use of prosthesis splinting and fixation type were evaluated for each implant. In peri-implant evaluation, minimum keratinized tissue width around implants, peri-implant probing depths, peri-implant bleeding and peri-implant suppuration were assessed. Bone resorption around implants was evaluated with intraoral radiographs at baseline and at follow-up examinations. The study endpoint was peri-implantitis, which was defined as the presence of bleeding on probing and/or suppuration with bone resorption >1mm, in accordance with previous studies. Data were analyzed with mixed-effects Cox models.

RESULTS

Peri-implantitis occurred in 15.3% of patients and 9.2% of implants. The overall 5- and 10-year cumulative implant survival rates were 0.95 (95% confidence interval [CI]: 0.93-0.96) and 0.83 (95% CI: 0.8-0.87), respectively. Age (hazard ratio [HR]=0.94, 95% CI: 0.90-0.98, p<0.01), plaque control record >20% (HR=2.61, 95% CI: 1.02-6.67, p=0.04), maxillary placement (HR=1.90, 95% CI: 1.11-3.23, p=0.02) and number of occlusal supports (HR=0.87, 95% CI: 0.77-0.99, p=0.03) were significantly correlated with peri-implantitis development.

CONCLUSIONS

Within the limitations of this longitudinal study on risk indicators for peri-implantitis, age, inadequate plaque control, insertion in the maxilla and less occlusal support of natural teeth correlated with peri-implantitis development.

摘要

目的

本研究旨在评估种植体周围炎的发生率,并确定潜在的相关风险指标。

方法

本纵向研究纳入了 477 名患者的 1420 枚种植体。所有患者均评估了其医疗和牙科病史。对每枚种植体的位置、大小、连接类型、手术方案、修复体夹板的使用以及固定类型进行了评估。在种植体周围评估中,评估了种植体周围最小角化组织宽度、种植体探诊深度、种植体出血和种植体溢脓。在基线和随访检查时,通过口腔内射线评估了种植体周围的骨吸收情况。研究终点为种植体周围炎,其定义为探诊时出血和/或溢脓伴有骨吸收>1mm,这与之前的研究一致。采用混合效应 Cox 模型对数据进行分析。

结果

15.3%的患者和 9.2%的种植体发生了种植体周围炎。总的 5 年和 10 年种植体累积存活率分别为 0.95(95%置信区间:0.93-0.96)和 0.83(95%置信区间:0.8-0.87)。年龄(风险比[HR]=0.94,95%置信区间:0.90-0.98,p<0.01)、菌斑控制记录>20%(HR=2.61,95%置信区间:1.02-6.67,p=0.04)、上颌骨植入(HR=1.90,95%置信区间:1.11-3.23,p=0.02)和咬合支持数(HR=0.87,95%置信区间:0.77-0.99,p=0.03)与种植体周围炎的发生显著相关。

结论

在这项关于种植体周围炎风险指标的纵向研究中存在一定的局限性,但本研究表明,年龄、菌斑控制不足、上颌骨植入以及天然牙咬合支持减少与种植体周围炎的发生有关。

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