Higuera-Cárdenas Jesús M, Román-Matus Alexis, Martínez-Contreras Angélica M, Haro-Acosta María E
Hospital General de Zona 30. Instituto Mexicano del Seguro Social, Baja California, México.
Delegación Baja California. Instituto Mexicano del Seguro Social, Baja California, México.
Cir Cir. 2019;87(1):96-100. doi: 10.24875/CIRU.18000330.
Langerhans cell histiocytosis is a rare disease in the adult, predominates in the pediatric age and is more common in men than in women. The sites of greater affection are the long bones, followed by the bones of the skull. Patients usually have symptoms related to the site of affection, usually polyostotic lesions, monostotic lesions occur less frequently. The study of choice and treatment depends on the site affected, in the skull the main one is the magnetic resonance and the treatment is the surgical excision of the lesion.
A 29-year-old female patient who entered the hospital due to a non-painful, rapidly growing, progressive tumor on the frontal region of the skull. Physical examination revealed a rounded mass of approximately 5 cm in diameter in the left, non-painful, non-painful, left-frontoparietal region. Magnetic resonance imaging of the skull showed a lytic lesion in the frontal bone. It was surgically excised with clean edges; titanium plate was placed. Histopathological diagnosis was histiocytosis of Langerhans cells.
It is a rare case, with a patient of an uncommon age of presentation, absence of metastasis by means of study protocol and due to the monostotic presentation improves the prognosis for this patient.
朗格汉斯细胞组织细胞增多症在成人中是一种罕见疾病，在儿童期更为常见，男性比女性更易患病。受累较多的部位是长骨，其次是颅骨。患者通常有与受累部位相关的症状，通常为多骨病变，单骨病变较少见。检查和治疗的选择取决于受累部位，在颅骨中主要检查方法是磁共振成像，治疗方法是手术切除病变。
一名29岁女性患者因颅骨额部出现无痛、快速生长、进行性肿物入院。体格检查发现左额顶叶区域有一个直径约5厘米的圆形肿物，无痛。颅骨磁共振成像显示额骨有溶骨性病变。手术切除肿物，切缘干净；置入钛板。组织病理学诊断为朗格汉斯细胞组织细胞增多症。
这是一例罕见病例，患者发病年龄不常见，根据研究方案未发现转移，且由于单骨病变表现改善了该患者的预后。
