噬菌体展示：药物发现背景下的概述。
Phage Display: An Overview in Context to Drug Discovery.
机构信息
Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.
Department of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Catanzaro, Italy.
出版信息
Trends Pharmacol Sci. 2019 Feb;40(2):87-91. doi: 10.1016/j.tips.2018.12.005. Epub 2018 Dec 31.
PMID:30606501
Abstract
Peptides are emerging as a new reliable class of therapeutics and, thanks to their lower cost of production, they are becoming established as perfect drug aspirants. Here, we briefly review the phage display method and its contribution to the identification of peptides of interest for the therapeutic market.
摘要
肽类正在成为一类新的可靠治疗药物，由于其生产成本较低，它们已成为理想的药物候选物。在这里，我们简要回顾噬菌体展示方法及其对鉴定治疗市场中感兴趣的肽类的贡献。
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