Dhopte Ashwini, Naidu Giridhar, Singh-Makkad Ramanpal, Nagi Ravleen, Bagde Hiroj, Jain Supreet
Post Graduate Student, Department of Oral Medicine and Radiology.
Professor and Head of the Department, Department of Oral Medicine and Radiology.
J Clin Exp Dent. 2018 Nov 1;10(11):e1109-e1114. doi: 10.4317/jced.55012. eCollection 2018 Nov.
Recurrent Aphthous Stomatitis is a chronic inflammatory immune mediated condition associated with single or multiple, painful recurring ulcers of the oral mucosa. Psychological stress is a common trigger factor identified for the onset and progression of this condition. The study aimed to evaluate stress, anxiety and depression using the Hospital Anxiety and Depression scale and stress by the General Health Questionnaire in subjects with Recurrent Aphthous Stomatitis (RAS).
The study evaluated subjects with a history of Recurrent Aphthous Stomatitis and compared their psychological stress, anxiety and depression alteration to normal subjects. Seventy-five study subjects were divided into three groups; test group 1 (25 subjects) presenting with RAS, test group 2 (25 subjects) with a history of RAS but without oral ulcers, and 25 normal subjects with no history of RAS formed the control group. Chi square and student t test was used to determine the relationship between psychological variables and recurrent aphthous ulcers.
Comparison of stress, Anxiety and Depression between test group 1 and control group, test group 2 and control group was not found to be statistically significant (< 0.05). Hence, differences were evident when individual questions were analyzed for stress anxiety and depression. Stress and depression were more prevalent in females, students and patients with a history of RAS.
Higher depression and stress levels were evident in subjects with a history of RAS. Psychological stress is a utmost trigger factor for the initiation of recurrent ulcers. Overall, test group patients had a more psychological impact on the quality of life than the control group. Anxiety, depression, General Health Questionnaire, Hospital Anxiety and Depression scale, Recurrent Aphthous Stomatitis, stress.
复发性阿弗他口炎是一种慢性炎症性免疫介导疾病，与口腔黏膜单个或多个疼痛性复发性溃疡相关。心理压力是已确定的该疾病发作和进展的常见触发因素。本研究旨在使用医院焦虑抑郁量表评估复发性阿弗他口炎（RAS）患者的压力、焦虑和抑郁情况，并通过一般健康问卷评估其压力水平。
本研究对有复发性阿弗他口炎病史的受试者进行评估，并将他们的心理压力、焦虑和抑郁变化与正常受试者进行比较。75名研究对象分为三组；试验组1（25名受试者）患有RAS，试验组2（25名受试者）有RAS病史但无口腔溃疡，25名无RAS病史的正常受试者组成对照组。采用卡方检验和学生t检验来确定心理变量与复发性阿弗他溃疡之间的关系。
试验组1与对照组、试验组2与对照组之间的压力、焦虑和抑郁比较未发现具有统计学意义（<0.05）。因此，在分析压力、焦虑和抑郁的各个问题时差异明显。压力和抑郁在女性、学生以及有RAS病史的患者中更为普遍。
有RAS病史的受试者中抑郁和压力水平较高。心理压力是复发性溃疡发作的最主要触发因素。总体而言，试验组患者对生活质量的心理影响比对照组更大。焦虑、抑郁、一般健康问卷、医院焦虑抑郁量表、复发性阿弗他口炎、压力。
