Hamza Naseer Hameed
a Mechanical Engineering Department , University of Al-Qadisiyah , Ad'Diwaniya , Iraq.
J Med Eng Technol. 2018 Aug;42(6):475-481. doi: 10.1080/03091902.2018.1546344. Epub 2019 Jan 4.
One method of removing malignant tissues from human organs is radiofrequency ablation. Thermal radiofrequency is a common technique of liver tumour therapy, which depends mainly on heating the infected region. This work proposes to investigate the thermal issue, which - in instance of excessive current - leads to extra lesion in liver tissues. However, the thermal lesions and the mistakes occurred in positioning the trocar instrument in the correct and accurate place arise the need to simulate and prediction of the thermal and electrical behaviour of the ablation operation. By using COMSOL multiphysics package, the process of hepatic tumour ablation has been simulated. Results show that by virtue of higher blood electrical conductivity, the nearby liver tissue around the electrode can be heated by rising its temperature due to electrical current from the radiofrequency probe according to the Joule law. Also, in this paper, different values of blood perfusion rate have been applied in the simulation process to investigate its effect on the ablation process. It is found that the increasing of mass flow rate of blood flow tends to bring down the fraction of necrotic tissue, which is contraindicated to the tumour ablation process.
从人体器官中切除恶性组织的一种方法是射频消融。热射频是肝脏肿瘤治疗的常用技术,主要依靠加热感染区域。这项工作旨在研究热问题,即在电流过大的情况下,会导致肝脏组织出现额外损伤。然而,热损伤以及在将套管针仪器正确、精确地放置在合适位置时出现的失误,引发了对模拟和预测消融操作的热行为和电行为的需求。通过使用COMSOL多物理场软件包,对肝肿瘤消融过程进行了模拟。结果表明,由于血液具有较高的电导率,根据焦耳定律,来自射频探头的电流会使电极周围的肝脏组织升温,从而被加热。此外,本文在模拟过程中应用了不同的血液灌注率值,以研究其对消融过程的影响。研究发现,血流质量流率的增加往往会降低坏死组织的比例,这与肿瘤消融过程是相悖的。