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采用氢氧化钙和MM-MTA的再生性牙髓治疗方案治疗患有根尖周炎的未成熟坏死恒牙:一项两年随访的病例报告

Management of an Immature Necrotic Permanent Molar with Apical Periodontitis Treated by Regenerative Endodontic Protocol Using Calcium Hydroxide and MM-MTA: A Case Report with Two Years Follow Up.

作者信息

Ajram Jessy, Khalil Issam, Gergi Richard, Zogheib Carla

机构信息

Faculty of Dentistry, Department of Endodontics, Saint Joseph University, Beirut 1107-2180, Lebanon.

Head of Department of Endodontics, Saint Joseph University, Beirut 1107-2180, Lebanon.

出版信息

Dent J (Basel). 2019 Jan 1;7(1):1. doi: 10.3390/dj7010001.

Abstract

Traditionally, immature teeth diagnosed with necrotic pulp and periapical periodontitis were treated by apexification with long-term calcium hydroxide or in one session with mineral trioxide aggregate (MTA) or Biodentine apical plug. However, these teeth become fragile and susceptible to root fracture. Regenerative endodontic procedure is a new therapeutic approach that promotes continuation of root growth in immature necrotic teeth potentially preventing root fracture. Only few case reports have shown the success of this procedure on molar cases. The current case report demonstrates a regeneration of a lower first molar with necrotic pulp and chronic apical abscess treated with Micro Mega-MTA (MM-MTA), a new endodontic biomaterial that has not been described previously. Calcium hydroxide was used as an intracanal medicament for two weeks. Next, calcium hydroxide was removed and after blood clot creation, MM-MTA was placed over it. Apical healing and continuation of root growth were evident at nine months follow-up. CBCT at two years follow-up confirmed apical closure and complete healing. This case shows that a regenerative endodontic procedure for management of an immature necrotic permanent molar is feasible and can be successfully done using Ca(OH)₂ and MM-MTA.

摘要

传统上,诊断为牙髓坏死和根尖周炎的未成熟牙齿通过长期使用氢氧化钙进行根尖诱导成形术,或一次性使用三氧化矿物凝聚体(MTA)或生物陶瓷根尖充填材料进行治疗。然而,这些牙齿会变得脆弱且易发生牙根折断。牙髓再生治疗是一种新的治疗方法,可促进未成熟坏死牙齿的牙根继续生长,有可能预防牙根折断。仅有少数病例报告显示该方法在磨牙病例中取得了成功。本病例报告展示了一例用新型牙髓生物材料Micro Mega-MTA(MM-MTA)治疗的下颌第一磨牙牙髓坏死和慢性根尖脓肿的再生情况,此前尚未有关于该材料的描述。使用氢氧化钙作为根管内药物两周。接下来,去除氢氧化钙,形成血凝块后,在其上放置MM-MTA。九个月随访时可见根尖愈合和牙根继续生长。两年随访时的锥形束计算机断层扫描(CBCT)证实根尖封闭且完全愈合。该病例表明,使用氢氧化钙和MM-MTA对未成熟坏死恒牙进行牙髓再生治疗是可行的,并且可以成功实施。

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