Schwarze G, Dietz R
Medizinische Universitätsklinik Homburg/Saar.
Strahlenther Onkol. 1988 Dec;164(12):746-51.
The production of antibodies against heterologous erythrocytes (sheep erythrocytes) can be significantly increased in mice and rats by total body irradiation. This effect depends upon the radiation dose applied and can be demonstrated only in animals immunized first and then irradiated at intervals of six hours. In vitro assays show indirectly that the radiogenic immune stimulation is caused by the varying radiosensitivity of the individual cell populations involved in the humoral immune reaction, leading to a relatively selective inactivation of T-suppressor cells.
通过全身照射，小鼠和大鼠体内针对异种红细胞（绵羊红细胞）的抗体产生量可显著增加。这种效应取决于所施加的辐射剂量，并且只有在首先免疫然后每隔六小时进行照射的动物中才能表现出来。体外试验间接表明，辐射诱导的免疫刺激是由体液免疫反应中各个细胞群体不同的放射敏感性引起的，导致T抑制细胞相对选择性失活。
