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[马急性蹄叶炎的发病机制与药物治疗:文献综述]

[Pathogenesis and drug therapy of acute laminitis in horses: a literature review].

作者信息

Boosman R, Németh F

机构信息

Vakgroep Algemene Heelkunde en Heelkunde der Grote Huisdieren, Utrecht.

出版信息

Tijdschr Diergeneeskd. 1988 Nov 15;113(22):1237-46.

PMID:3061064
Abstract

Impairment of the microcirculation in the distal part of the foot is an important factor in the aetiology of equine laminitis. To prevent the development of chronic laminitis and the resulting complications, two new therapeutical principles were tested in the treatment of acute laminitis. Thrombosis which frequently occurs in the corium of the foot, could be controlled by administration of anticoagulants such as heparin. Alpha-receptor blocking agents such as phenoxybenzamine were used, to improve the peripheral blood flow. The use of these drugs and that of anti-inflammatory agents during the onset of acute laminitis is discussed in this review paper.

摘要

马蹄远端微循环障碍是马属动物蹄叶炎病因学中的一个重要因素。为预防慢性蹄叶炎的发展及其引发的并发症,在急性蹄叶炎的治疗中对两项新的治疗原则进行了试验。足部真皮层频繁发生的血栓形成可通过给予肝素等抗凝剂来控制。使用苯苄胺等α受体阻滞剂来改善外周血流。本文综述了在急性蹄叶炎发作期间使用这些药物以及抗炎药的情况。

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