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教育程度与妊娠结局:一项基于丹麦登记册的研究,探讨儿童时期社会劣势对人工流产、自然流产、死产和早产后期社会经济差异的影响。

Educational Attainment and Pregnancy Outcomes: A Danish Register-Based Study of the Influence of Childhood Social Disadvantage on Later Socioeconomic Disparities in Induced Abortion, Spontaneous Abortion, Stillbirth and Preterm Delivery.

作者信息

Hegelund Emilie Rune, Poulsen Gry Juul, Mortensen Laust Hvas

机构信息

Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, P.O. Box 2099, 1014, Copenhagen K, Denmark.

出版信息

Matern Child Health J. 2019 Jun;23(6):839-846. doi: 10.1007/s10995-018-02704-1.

Abstract

Objectives Socioeconomic disparities in pregnancy outcomes have been found across times and places, but there is a lack of studies investigating the underlying causes. The present study investigated the influence of child protective services in the pregnant woman's family of origin as a proxy of childhood social disadvantage. Methods The study population comprised all registered pregnancies in Denmark during the period from 2000 to 2009 that resulted in an induced abortion, spontaneous abortion, stillbirth or live birth (N = 786,054). Linear regression was used to analyze the associations between educational attainment and pregnancy outcomes in models with and without adjustment for age, parental educational attainment and child protective services in the family of origin. Further, it was tested whether child protective services in the pregnant woman's family of origin modified the associations between educational attainment and pregnancy outcomes. Results Women with low educational attainment had a higher risk of induced abortion, stillbirth and preterm delivery and a lower risk of spontaneous abortion. These associations were to some extent explained by child protective services in the family of origin. Further, child protective services in the pregnant woman's family of origin modified the association between educational attainment and risk of preterm delivery. Thus, women with high educational attainment were not found to differ in risk of preterm delivery according to child protective services in the family of origin Conclusions for Practice Information on childhood social disadvantage may enrich our understanding of the socioeconomic disparities in pregnancy outcomes.

摘要

目标 不同时期和不同地点均发现了妊娠结局方面的社会经济差异,但缺乏对其潜在原因的研究。本研究调查了孕妇原生家庭中的儿童保护服务作为童年社会劣势的一个指标所产生的影响。方法 研究人群包括2000年至2009年期间丹麦所有登记的妊娠,这些妊娠导致人工流产、自然流产、死产或活产(N = 786,054)。在未调整年龄、父母教育程度和原生家庭中的儿童保护服务的模型以及调整后的模型中,使用线性回归分析教育程度与妊娠结局之间的关联。此外,还测试了孕妇原生家庭中的儿童保护服务是否改变了教育程度与妊娠结局之间的关联。结果 教育程度低的女性人工流产、死产和早产的风险较高,自然流产的风险较低。这些关联在一定程度上可由原生家庭中的儿童保护服务来解释。此外,孕妇原生家庭中的儿童保护服务改变了教育程度与早产风险之间的关联。因此,未发现教育程度高的女性在早产风险方面因原生家庭中的儿童保护服务而存在差异 实践结论 关于童年社会劣势的信息可能会丰富我们对妊娠结局社会经济差异的理解。

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