Fang C H, Chen K, Zhang P
First Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University; Guangdong Provincial Clinical and Engineering Center of Digital Medicine, Guangzhou 510282, China.
Zhonghua Wai Ke Za Zhi. 2019 Jan 1;57(1):1-5. doi: 10.3760/cma.j.issn.0529-5815.2019.01.001.
With the development of the times, a series of innovative intelligent diagnosis and treatment techniques have emerged, providing new strategies and means for disease diagnosis and treatment, which is helpful for promoting the development of general surgery in China. This article, combined with relevant literature at home and abroad, reviews the application of digital medical intelligent diagnosis and treatment technologies in general surgery,such as three-dimensional visualization,three-dimentional printing, mixed reality, molecular fluorescence imaging, artificial intelligence-imaging omics, abdominal surgery navigation and photoacoustic imaging. Three-dimentional visualization has changed the traditional "two-dimensional" disease diagnosis and treatment mode; three-dimentional printing of three-dimentional images is a leap-forward transition to stereoscopic physical models; mixed reality has broken the boundary between the digital virtual world and the physical real world, bringing technological innovation to traditional surgery; Indocyanine green molecular fluorescence imaging has achieved tumor boundary definition, micro or metastatic lesion detection and intraoperative real-time navigation at the molecular and cellular level; artificial intelligence-imaging omics can improve the accuracy of disease diagnosis and predict risk and efficacy; abdominal surgical navigation can improve the accuracy and safety of the operation; high precision-cross-scale photoacoustic microscopy can define the tumor boundary from the molecular, cellular and microvascular levels to guide the precise resection of the tumor; finally, this paper looks forward to the new direction of general surgery diagnosis and treatment represented by digital medicine and artificial intelligence.
随着时代的发展,一系列创新的智能诊断和治疗技术应运而生,为疾病的诊断和治疗提供了新的策略和手段,有助于推动我国普通外科的发展。本文结合国内外相关文献,综述了数字医学智能诊断和治疗技术在普通外科中的应用,如三维可视化、三维打印、混合现实、分子荧光成像、人工智能-影像组学、腹部手术导航和光声成像。三维可视化改变了传统的“二维”疾病诊断和治疗模式;三维图像的三维打印是向立体物理模型的跨越式转变;混合现实打破了数字虚拟世界与物理现实世界之间的界限,给传统手术带来了技术创新;吲哚菁绿分子荧光成像在分子和细胞水平上实现了肿瘤边界界定、微小或转移病灶检测及术中实时导航;人工智能-影像组学可提高疾病诊断的准确性并预测风险和疗效;腹部手术导航可提高手术的准确性和安全性;高精度跨尺度光声显微镜能从分子、细胞和微血管水平界定肿瘤边界,指导肿瘤的精准切除;最后,本文展望了以数字医学和人工智能为代表的普通外科诊断和治疗的新方向。